93717-55-6 (2-氰基-4'-甲基联苯,4'-Methyl-[1,1'-biphenyl]-2-carbonitrile)

快速询单

结构式：

2-氰基-4'-甲基联苯MOL文件

CAS号：

93717-55-6

中文名称：

2-氰基-4'-甲基联苯

英文名称：

4'-Methyl-[1,1'-biphenyl]-2-carbonitrile

分子式：

C₁₄H₁₁N

分子量：

193.243843317032

2-氰基-4'-甲基联苯(93717-55-6)名称与标识符

名称

中文别名：

2-氰基-4'-甲基联苯;沙坦联苯;4'-甲基-2-腈基联苯;4-甲基-2-氰基联苯;2-(4’-甲苯基)苯腈;甲基联苯;4‘-甲基-3-氰基联苯;2-氰基-4'-甲基联苯基;2-氰基-4-甲基联苯;2-氰基-4’-甲基联苯 (OTBN);2-氰基-4甲基联苯;2-氰基-4''-甲基联苯;

英文别名：

4'-Methyl-[1,1'-biphenyl]-2-carbonitrile;OTBN;2-cyano-4-methylbiphenyl;2-CYANO-4'-METHYL BIPHENYL;4'-methyl-2-cyano-biphenyl (for Losartan);AKOS BAR-1203;4'-METHYLBIPHENYL-2-CARBONITRILE;4'-METHYL-2-BIPHENYLCARBONITRILE;4'-METHYL-2-CYANOBIPHENYL;4'-METHYL[1,1'-BIPHENYL]-2-CARBONITRILE;2-(4-TOLYL)-BENZONITRILE;2-(4-METHYLPHENYL)BENZONITRILE;[2-(P-TOLYL)BENZONITRILE];2-Cyano-4'-methylbiphenyl (OTBN);3-(phenylmethyl)Benzonitrile;m-Tolunitrile,a-phenyl- (7CI);3-Benzylbenzonitrile;3-(Phenylmethyl)benzonitrile (ACI);m-Tolunitrile, α-phenyl- (7CI);

标识符

MDL：

MFCD06411093

InChIKey：

GOFIMQVJGKCLGF-UHFFFAOYSA-N

Inchi：

1S/C14H11N/c15-11-14-8-4-7-13(10-14)9-12-5-2-1-3-6-12/h1-8,10H,9H2

SMILES：

N#CC1C=C(CC2C=CC=CC=2)C=CC=1

2-氰基-4'-甲基联苯(93717-55-6)物化性质

实验特性

熔点 : 49-53 °C

2-氰基-4'-甲基联苯(93717-55-6)安全信息

2-氰基-4'-甲基联苯(93717-55-6)推荐厂家更多厂家(45)

公司名称	手机号/电话	联系人	QQ	询单
江苏新素新材料有限公司	13914000513 0512-66387919	孙文婷	3771156959	询单
天门恒昌化工有限公司	15102714773 027-59322316	雷经理	1178380033	询单
江苏雷恩环保科技有限公司	18662920632 0513-66017275	费小姐	3485543679	询单
湖北摆渡化学有限公司	13517219350 13517219350	彭星	1400878899	询单
湖北永阔科技有限公司	18064098002 027-59223108	孙瑶	1248580055	询单
巨胜化学研究院	18064118002 027-59599240	陈盼	1400838822	询单
湖北万得化工有限公司	15827180502 027-59210159	陈丹丹	1148980033	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364	询单
湖北信康药化有限公司化学研究所	18827031272 027-59308705	张欢	1438980011	询单
湖北鑫红利化工有限公司	15172537016 027-59503710	祝雨薇	1018283355	询单

2-氰基-4'-甲基联苯(93717-55-6)合成路线

合成路线：1 步

329976-73-0

6952-59-6

_98%

93717-55-6

反应条件：

1.1 Reagents: Diisopropylethylamine Catalysts: Nickel, (2,2′-bipyridine-κN1,κN1′)dichloro-, (SP-4-2)- (functionalized with carbon nitride) Solvents: Tetrahydrofuran ; 36 h, rt

参考文献：

Heterogeneous Metallaphotocatalytic C(sp2)-C(sp3) Cross-Coupling Reactions with Integrated Bipyridyl-Ni(II)-Carbon Nitride

Dan, Xiao ; Yang, Qian ; Xing, Liuzhuang ; Tang, Yurong ; Wang, Wentao ; et al, Organic Letters, 2023, 25(22), 4124-4129

合成路线：1 步

6952-59-6

100-44-7

_97%

93717-55-6

反应条件：

1.1 Reagents: Trifluoroacetic acid , Allyl chloride , Zinc Catalysts: Cobalt dibromide Solvents: Acetonitrile ; 3 min, rt
1.2 rt

参考文献：

Synthesis of functionalized diarylmethanes via a cobalt-catalyzed cross-coupling of arylzinc species with benzyl chlorides

Amatore, Muriel; Gosmini, Corinne, Chemical Communications (Cambridge, 2008, (40), 5019-5021

合成路线：1 步

2823404-26-6

640-60-8

_88%

93717-55-6

反应条件：

1.1 Catalysts: Dichlorobis(triphenylphosphine)palladium , 2′-[Bis(1-methylethyl)phosphino]-6-methoxy-N,N-dimethyl[1,1′-biphenyl]-2-amine Solvents: 2-Methyltetrahydrofuran ; 15 min, rt; rt → 80 °C; 6 h, 80 °C
1.2 Reagents: Water

参考文献：

Synthesis of Diarylmethanes via Pd-Catalyzed Coupling of Aryltosylates with Benzyltitanium Reagents

Zhang, He, Russian Journal of General Chemistry, 2022, 92(7), 1340-1347

合成路线：1 步

10406-24-3

98-80-6

_87%

93717-55-6

反应条件：

1.1 Reagents: Isoamyl nitrite , Sodium carbonate Solvents: Chloroform ; 24 h, 60 °C

参考文献：

Deaminative coupling of benzylamines and arylboronic acids

Sirvinskaite, Giedre; Reisenbauer, Julia C.; Morandi, Bill, Chemical Science, 2023, 14(7), 1709-1714

合成路线：1 步

1644578-02-8

69113-59-3

_72%

93717-55-6

反应条件：

1.1 Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Tetrahydrofuran ; 1 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ; rt

参考文献：

Alternative Approach toward the Generation of Benzylic Zinc Reagent: Direct Oxidative Addition of Active Zinc into the Carbon-Oxygen Bond of Benzyl Mesylates

Jung, Hye-Soo; Kim, Seung-Hoi, Synlett, 2015, 26(5), 666-670

合成路线：1 步

150255-96-2

100-39-0

_71%

93717-55-6

反应条件：

1.1 Reagents: Potassium carbonate , Oxygen Catalysts: 2242836-60-6 Solvents: Ethanol , Water ; 5 h, 60 °C

参考文献：

Picolinamide modified β-cyclodextrin/Pd (II) complex: Asupramolecular catalyst for Suzuki-Miyaura coupling of aryl, benzyl and allyl halides with arylboronic acids in water

Luo, Kaixiu; Zhang, Lu; Yang, Rui; Jin, Yi ; Lin, Jun, Carbohydrate Polymers, 2018, 200, 200-210

合成路线：1 步

28188-41-2

98-80-6

_71%

93717-55-6

反应条件：

1.1 Reagents: Sodium carbonate , Tri-o-tolylphosphine Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Acetonitrile , Water ; 2 h, reflux; reflux → rt

参考文献：

Preparation of 4,5-dihydro-1,2,4-triazin-6-ones and 1,2,4-trianzin-6-ones for use as fungicides

, World Intellectual Property Organization, , ,

合成路线：1 步

27798-39-6

557-21-1

_69%

93717-55-6

反应条件：

1.1 Catalysts: Tetrakis(triphenylphosphine)palladium Solvents: Dimethylformamide ; 2 d, 95 °C

参考文献：

Preparation of hydrazide, amide, phthalimide and phthalhydrazide analogs as inhibitors of retroviral integrase

, World Intellectual Property Organization, , ,

合成路线：1 步

93717-55-6

参考文献：

The effect of meta- or para-cyano substitution on the reactivity of the radical cations of arylalkenes and alkanes. Radical ions in photochemistry. Part 34

Arnold, Donald R.; Du, Xinyao; Chen, Jing, Canadian Journal of Chemistry, 1995, 73(3), 307-18