948592-80-1 (2-氨基-5-甲基苯硼酸频那醇酯,2-Amino-5-methylphenyboronic Acid Pinacol Ester)

_99%

反应条件：

1.1 Reagents: Potassium acetate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; 6 h, 105 °C

参考文献：

Palladium-Catalyzed Four-Component Cascade Imidoyl-Carbamoylation of Unactivated Alkenes

Cheng, Sidi; Luo, Yu; Yu, Ting; Li, Jing; Gan, Chunfang; et al, ACS Catalysis, 2022, 12(2), 837-845

合成路线：1 步

_94%

反应条件：

1.1 Reagents: Potassium acetate Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: Dimethyl sulfoxide ; overnight, 80 °C

参考文献：

Preparation of macrocycles with aromatic p2' groups as factor XIa inhibitors

, World Intellectual Property Organization, , ,

合成路线：1 步

_94%

反应条件：

1.1 Reagents: Potassium acetate Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: Dimethyl sulfoxide ; overnight, 80 °C

参考文献：

Preparation of macrocycles with heterocyclic p2' groups as factor XIa inhibitors

, World Intellectual Property Organization, , ,

合成路线：1 步

_89%

反应条件：

1.1 Reagents: Triethylamine Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: 1,4-Dioxane ; rt; 12 h, 120 °C

参考文献：

Efficient Synthesis of 3H-Indoles Enabled by the Lead-Mediated α-Arylation of β-Ketoesters or γ-Lactams Using Aryl Azides

Zhou, Fei; Driver, Tom G., Organic Letters, 2014, 16(11), 2916-2919

合成路线：1 步

_85%

反应条件：

1.1 Reagents: Triethylamine Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: 1,4-Dioxane ; rt; 19 h, 120 °C; 120 °C → rt
1.2 Reagents: Ammonium chloride Solvents: Water

参考文献：

Regiodivergent Synthesis of 11H-Indolo[3,2-c]quinolines and Neocryptolepine from a Common Starting Material

Haaheim, Katja S.; Lund, Bjarte Aarmo; Sydnes, Magne O., European Journal of Organic Chemistry, 2023, 26(13),

合成路线：1 步

_85%

反应条件：

1.1 Reagents: Potassium acetate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; 5 min, rt
1.2 10 h, reflux

参考文献：

Method for the preparation of homologous ligand iridium complexes containing DMP as a ligand structure using microwave for phosphorescent light-emitting devices

, Korea, , ,

合成路线：1 步

_80%

反应条件：

1.1 Reagents: Potassium acetate Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: 1,4-Dioxane ; 16 h, 100 °C

参考文献：

Microwave assisted synthesis of phenanthridine derivatives via Suzuki coupling and condensation

Dende, Satheesh Kumar; Korupolu, Raghu Babu; Doddipalla, Raju; Leleti, Krishnakanth Reddy, Results in Chemistry, 2021, 3,

合成路线：1 步

_71%

反应条件：

1.1 Reagents: Triethylamine Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; rt; rt → 100 °C; 12 h, 100 °C

参考文献：

I(III)-Catalyzed Oxidative Cyclization-Migration Tandem Reactions of Unactivated Anilines

Deng, Tianning; Shi, Emily; Thomas, Elana; Driver, Tom G., Organic Letters, 2020, 22(22), 9102-9106

合成路线：1 步

_71%

反应条件：

1.1 Reagents: Triethylamine Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; rt; rt → 100 °C; 12 h, 100 °C

参考文献：

Oxidation of Non-Activated Anilines to Generate N-Aryl Nitrenoids

Deng, Tianning; Mazumdar, Wrickban; Ford, Russell L.; Jana, Navendu ; Izar, Ragda; et al, Journal of the American Chemical Society, 2020, 142(9), 4456-4463

合成路线：1 步

29289-13-2

_63%

反应条件：

1.1 Reagents: Triethylamine Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: 1,4-Dioxane ; 5 h, 100 °C

参考文献：

New synthetic approach to paullones and characterization of their SIRT1 inhibitory activity

Soto, Sara; Vaz, Esther; Dell'Aversana, Carmela; Alvarez, Rosana; Altucci, Lucia; et al, Organic & Biomolecular Chemistry, 2012, 10(10), 2101-2112

合成路线：1 步

_55%

反应条件：

1.1 Reagents: Triethylamine Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; 12 h, rt → 100 °C

参考文献：

Rh2(II)-Catalyzed Ester Migration to Afford 3H-Indoles from Trisubstituted Styryl Azides

Kong, Chen; Driver, Tom G., Organic Letters, 2015, 17(4), 802-805

合成路线：1 步

_42%

反应条件：

1.1 Reagents: Triethylamine Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; 12 h, 120 °C

参考文献：

Control of the Chemoselectivity of Metal N-Aryl Nitrene Reactivity: C-H Bond Amination versus Electrocyclization

Kong, Chen; Jana, Navendu; Jones, Crystalann; Driver, Tom G., Journal of the American Chemical Society, 2016, 138(40), 13271-13280

合成路线：1 步

_42%

反应条件：

1.1 Reagents: Triethylamine Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; 120 °C; 12 h, 120 °C

参考文献：

Development of a Suzuki Cross-Coupling Reaction between 2-Azidoarylboronic Pinacolate Esters and Vinyl Triflates To Enable the Synthesis of [2,3]-Fused Indole Heterocycles

Jana, Navendu; Nguyen, Quyen; Driver, Tom G., Journal of Organic Chemistry, 2014, 79(6), 2781-2791

合成路线：1 步

_36%

反应条件：

1.1 Reagents: Triethylamine Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; 12 h, 120 °C; 120 °C → rt

参考文献：

Rh2(II)-Catalyzed Selective Aminomethylene Migration from Styryl Azides

Kong, Chen; Jana, Navendu; Driver, Tom G., Organic Letters, 2013, 15(4), 824-827

合成路线：1 步

_36%

反应条件：

1.1 Reagents: Triethylamine Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ; rt → 80 °C; 16 h, 80 °C

参考文献：

Rh2(II)-Catalyzed intramolecular aliphatic C-H bond amination reactions using aryl azides as the N-atom source

Nguyen, Quyen; Sun, Ke; Driver, Tom G., Journal of the American Chemical Society, 2012, 134(17), 7262-7265

合成路线：1 步