949-36-0 (盐酸异丙肾上腺素,1,2-Benzenediol,4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1))

CAS号:
949-36-0
中文名称:
盐酸异丙肾上腺素
英文名称:
1,2-Benzenediol,4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1)
分子式:
C11H18ClNO3
分子量:
247.718522548676

盐酸异丙肾上腺素(949-36-0)名称与标识符

名称

中文别名:
(±)-异丙基肾上腺素盐酸盐;盐酸异丙肾上腺素;
英文别名:
1,2-Benzenediol,4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1);ISOPROTERENOL HYDROCHLORIDE;asthpul;dl-isadrinehydrochloride;dl-isoprenalinehydrochloride;isoprenaline;ISOPRENALINE HCL;ISOPROPYLARTERENOL HYDROCHLORIDE;isoproterenol HCl;racemicisoprenalinehydrochloride;Saventrine IV;vapo-iso;ISOPROTERENOL HYDROCHLORIDE (USP MONOGRAPH);ISOPROTERENOL HYDROCHLORIDE [ORANGE BOOK];NORISODRINE-H;NCGC00258824-01;EINECS 200-089-8;EU-0100711;Tox21_500711;NSC-37745;alpha-(Isopropylaminomethyl)-3,4-dihydroxybenzyl alcohol hydrochloride;Isoproterenol monohydrochloride;Isopropylnorepinephrine-hydrochloride;DL-ISOPRENALINE HYDROCHLORIDE [JAN];(+-)-Isopropylnoradrenaline hydrochloride;1-(3',4'-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride;ISOPRENALINE HYDROCHLORIDE [EP MONOGRAPH];Isuprel (TN);s2566;ISOPRENALINE HYDROCHLORIDE (EP MONOGRAPH);MLS002153386;I 5627;4-(1-Hydroxy-2-(isopropylamino)ethyl)pyrocatechol hydrochloride;ISOPROTERENOL HYDROCHLORIDE (USP-RS);Proternol-S;NCGC00025274-02;Isoprenaline hydrochloride, dl-;l-Isoprenaline hydrochloride;REGID_for_CID_5807;IZADRINE-HYDROCHLORIDE;NCGC00094061-04;ISOPROTERENOL HYDROCHLORIDE [USP MONOGRAPH];3,4-DIHYDROXY-ALPHA-((ISOPROPYLAMINO)METHYL)-BENZYL ALCOHOL HYDROCHLORIDE;(+/-)-Isoproterenol hydrochloride;Isoproterenol (hydrochloride);.alpha.-(Isopropylaminomethyl)-3,4-dihydroxybenzyl alcohol hydrochloride;Proternol-S (TN);FT-0627456;NSC-89747;NCGC00025274-05;ISOPRENALINE HYDROCHLORIDE [WHO-DD];BCP9000796;SW197212-2;ISOPROTERENOL DL-FORM HYDROCHLORIDE;NSC 37745;NSC-757079;Benzenemethanol, 3,4-dihydroxy-alpha-(((1-methylethyl)amino)methyl)-, hydrochloride, (+/-)-;Isovon;DUO-MEDIHALER COMPONENT ISOPROTERENOL HYDROCHLORIDE;SPECTRUM1500357;dl-Isadrine hydrochloride;MLS001335893;1336-89-6;51-30-9;CAS-51-30-9;4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol Hydrochloride;Tox21_201272;NS00076358;3,4-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol hydrochloride;HMS1571K16;949-36-0;dl-Isoprenaline hydrochloride (JAN);NSC 89747;LP00711;Tox21_300308;ISOPREL;3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol hydrochloride;AI3-52675;1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, hydrochloride;I0260;Benzyl alcohol,4-dihydroxy-.alpha.-[(isopropylamino)methyl]-, hydrochloride, (+-)-;SMR000058267;1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride;Isoprenaline HCl;NSC89747;Isomenyl;Isuprel;Hydrochloride, Isoproterenol;SR-01000075272;SR-01000075272-1;N-Isopropyl-DL-noradrenaline hydrochloride;NCGC00094061-03;ISOPRENALINE HYDROCHLORIDE [WHO-IP];ISOPRENALINE HYDROCHLORIDE (MART.);D01390;4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride;( inverted question mark)-Isoproterenol hydrochloride;DIA2A74855;(.+-.)-Isoproterenol hydrochloride;FT-0635930;NCGC00254027-01;WLN: QR BQ DYQ1MY1&1 &GH;4-(1-HYDROXY-2-((METHYLETHYL)AMINO)ETHYL)-1,2-BENZENEDIOL HYDROCHLORIDE;(.+-.)-Isoprenaline hydrochloride;AKOS015895437;4-[1-hydroxy-2-(isopropylamino)ethyl]benzene-1,2-diol hydrochloride;Isuprel hydrochloride;1, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride;ISOPROTERENOL HYDROCHLORIDE [VANDF];3,4-Dihydroxy-.alpha.-[(isopropylamino)methyl]benzyl alcohol hydrochloride;MLS001304049;NIOSH/UX1780000;Sooner;Levisoprenaline (hydrochloride);DTXSID6025486;4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol hydrochloride;(.+-.)-Isopropylnoradrenaline hydrochloride;(-)-N-Isopropyl-L-noradrenaline hydrochloride;4-[1-Hydroxy-2-(isopropylamino)ethyl]-1,2-benzenediol;HY-B0468;CCG-40129;Pharmakon1600-01500357;Z1416254508;Isoprenaline chloride;Isoprenaline (hydrochloride);ISOPRENALINE HYDROCHLORIDE (EP IMPURITY);Q26840880;ISOPRENALINE HYDROCHLORIDE [MART.];NCGC00094061-02;AC-8688;NCI-C55630;Isoprenaline hydrochloride, European Pharmacopoeia (EP) Reference Standard;Euspiran;Isoproterenol hydrochloride, United States Pharmacopeia (USP) Reference Standard;ISOPROTERENOL DL-FORM HYDROCHLORIDE [MI];A828528;W-105908;4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol HCl;BCP0726000230;4-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol hydrochloride;DL-Isoproterenol hydrochloride;ALUDRINE HYDROCHLORIDE;NCGC00261396-01;ISOPROTERENOL HYDROCHLORIDE [USP-RS];CHEBI:31453;1-(3,4-DIHYDROXYPHENYL)-2-(ISOPROPYLAMINO)ETHANOL HYDROCHLORIDE;Benzyl alcohol,4-dihydroxy-.alpha.-[(isopropylamino)methyl]-, hydrochloride;Isoproterenol hydrochloride (USP);NCGC00094061-01;DL-Isoprenaline hydrochloride;Aerotrol;CHEMBL1711;NCGC00094033-02;SR-01000075272-3;Izadrin;ISOVON (CL);IROWCYIEJAOFOW-UHFFFAOYSA-N;(+-)-Isoprenaline hydrochloride;DL-Isopropylnoradrenaline hydrochloride;NSC37745;3,4-DIHYDROXY-ALPHA-(ISOPROPYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE;NC00515;1, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride, (+-)-;UX17800000;Benzyl alcohol,4-dihydroxy-.alpha.-[(isopropylamino)methyl]-, hydrochloride, (.+-.)-;4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;hydrochloride;MFCD00012603;VU0244462-4;CCRIS 5921;BCP23375;AS-13330;(R)-3,4-Dihydroxy-alpha-(isopropylaminomethyl)benzyl alcohol hydrochloride;Aerolone;Isoprenaline hydrochloride (VAN);1, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride, (.+-.)-;DTXCID105486;Suscardia;Norisodrine hydrochloride;H10806;Iprenol;(?)-Isoproterenol hydrochloride;Mistarel;component of Aerolone Compound;ISOINTRANEFRIN;Isoproterenol hydrochloride [USP];ISOPRENALINE HYDROCHLORIDE [EP IMPURITY];Isadrine-hydrochloride;ISOPROTERENOL HYDROCHLORIDE COMPONENT OF DUO-MEDIHALER;UNII-DIA2A74855;SCHEMBL7627;MFCD00064548;NSC757079;NCGC00094033-01;Norisodrine Aerotrol;Pyrocatechol, 4-(1-hydroxy-2-(isopropylamino)ethyl)-, hydrochloride;ISOPROPYDRINE HYDROCHLORIDE;EN300-108428;MLS001335894;DL-Isopropylnorepinephrine hydrochloride;(+-)-Isoproterenol hydrochloride;Isoprenaline hydrochloride;ISOPROTERENOLHYDROCHLORIDE;(y)-Isoproterenol hydrochloride;Isoprenaline Hydrochloride,(S);Benzyl alcohol, 3,4-dihydroxy-alpha-((isopropylamino)methyl)-, hydrochloride;HMS1920H13;

标识符

InChIKey:
IROWCYIEJAOFOW-UHFFFAOYSA-N
Inchi:
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
SMILES:
Cl.OC(C1C=CC(=C(C=1)O)O)CNC(C)C

盐酸异丙肾上腺素(949-36-0)物化性质

实验特性

  • LogP : 2.32210
  • PSA : 72.72000
  • 沸点 : 417.5°Cat760mmHg
  • 熔点 : 165-175 °C (dec.)(lit.)
  • 闪点 : 179.7°C
  • 密度 : 1.199

计算特性

  • 精确分子量 : 247.09800
  • 氢键供体数量 : 5
  • 氢键受体数量 : 4
  • 可旋转化学键数量 : 4
  • 同位素质量 : 247.097521
  • 重原子数量 : 16
  • 复杂度 : 187
  • 同位素原子数量 : 0
  • 确定原子立构中心数量 : 0
  • 不确定原子立构中心数量 : 1
  • 确定化学键立构中心数量 : 0
  • 不确定化学键立构中心数量 : 0
  • 共价键单元数量 : 2
  • 拓扑分子极性表面积 : 72.7

盐酸异丙肾上腺素(949-36-0)安全信息

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盐酸异丙肾上腺素(949-36-0) MSDS

基础信息

Name:Dl-isoproterenol hydrochloride 98% Material Safety Data Sheet
Synonym:DL-N-Isopropylnoradrenaline hydrochlorid
CAS:949-36-0
Section 1 - Chemical Product ? MSDS Name:Dl-isoproterenol hydrochloride 98% Material Safety Data Sheet
Synonym:DL-N-Isopropylnoradrenaline hydrochlorid

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS#Chemical NamecontentEINECS#
949-36-0DL-ISOPROTERENOL HYDROCHLORIDE98213-438-4
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Hygroscopic (absorbs moisture from the air).Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
? Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
? Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 949-36-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 175 deg C dec
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: in water: 1gr/3ml
Specific Gravity/Density:
Molecular Formula: C11H17NO3.HCl
Molecular Weight: 247.72

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials, dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 949-36-0: DO1930000 LD50/LC50:
CAS# 949-36-0: Inhalation, mouse: LC50 = 10 gm/m3; Oral, mouse: LD50 = 1260 mg/kg; Oral, rabbit: LD50 = 3070 mg/kg; Oral, rat: LD50 = >2 gm/kg.
Carcinogenicity:
DL-ISOPROTERENOL HYDROCHLORIDE - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 949-36-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 949-36-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 949-36-0 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A