95656-86-3 (6-氯乙酰基-1,4-苯并二恶烷,Tert-butyl N-(2-hydroxypropyl)carbamate)

_99%

反应条件：

1.1 Solvents: Dichloromethane ; 5 h, 30 °C

参考文献：

Preparation of azepanylsulfonyl diarylamides and related compounds for mono- and combination therapy of hepatitis B infections

, United States, , ,

合成路线：1 步

_99%

反应条件：

1.1 Catalysts: Triethylamine Solvents: Tetrahydrofuran ; 25 °C

参考文献：

Chemical blowing agent and thermally expandable thermoplastic composition

, World Intellectual Property Organization, , ,

合成路线：1 步

_99%

反应条件：

1.1 Solvents: Dichloromethane ; 5 h, 30 °C

参考文献：

Preparation of azepane derivatives and methods of treating hepatitis B infections

, World Intellectual Property Organization, , ,

合成路线：1 步

_99%

反应条件：

1.1 Solvents: Dichloromethane ; rt → 0 °C; 0 °C; 0.5 h, 0 °C; overnight, rt

参考文献：

Preparation of cyanopyrrolidine and cyanothiazolidine derivatives as insulin sensitizers and dipeptidyl peptidase-IV inhibitors

, China, , ,

合成路线：1 步

_98%

反应条件：

1.1 Solvents: Dichloromethane ; 0 °C; 2 h, rt

参考文献：

Preparation of 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one compounds and their use as negative allosteric modulators of mGluR2 receptors

, World Intellectual Property Organization, , ,

合成路线：1 步

_97%

反应条件：

1.1 Reagents: Triethylamine Solvents: Methanol ; rt; 30 min, 60 °C

参考文献：

Process for the preparation of enantiopure 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

, World Intellectual Property Organization, , ,

合成路线：1 步

_96%

反应条件：

1.1 Solvents: Acetonitrile ; rt; 3 h, rt

参考文献：

A Deeper Insight into the Postpolymerization Modification of Polypenta Fluorophenyl Methacrylates to Poly(N-(2-Hydroxypropyl) Methacrylamide)

Mohr, Nicole; Barz, Matthias; Forst, Romina; Zentel, Rudolf, Macromolecular Rapid Communications, 2014, 35(17), 1522-1527

合成路线：1 步

_96%

反应条件：

1.1 Solvents: Methanol , Water ; 3 h, rt

参考文献：

Preparation of aminobutanoic acid amide derivatives as dipeptidyl peptidase IV (DPPIV) inhibitors

, World Intellectual Property Organization, , ,

合成路线：1 步

_95%

反应条件：

1.1 Solvents: Dichloromethane ; rt; 18 h, rt

参考文献：

Multi-arm polymeric prodrug conjugates of pemetrexed-based compounds as drug delivery systems for lung cancer

, World Intellectual Property Organization, , ,

合成路线：1 步

_95%

反应条件：

1.1 Reagents: Triethylamine Solvents: Dichloromethane ; overnight, rt

参考文献：

Enantioselective synthesis of aziridines using asymmetric transfer hydrogenation as a precursor for chiral derivatives used as bonding agent for rocket solid propellants

Kawamoto, Aparecida M.; Wills, Martin, Quimica Nova, 2002, 25(6), 921-925

合成路线：1 步

_95%

反应条件：

1.1 Reagents: Triethylamine Solvents: Dichloromethane

参考文献：

Enantioselective synthesis of β-hydroxy amines and aziridines using asymmetric transfer hydrogenation of α-amino ketones

Kawamoto, Aparecida M.; Wills, Martin, Journal of the Chemical Society, 2001, (16), 1916-1928

合成路线：1 步

_93%

反应条件：

1.1 Solvents: Ethanol ; 12 h, rt

参考文献：

Hydrogen-Bonding-Driven Enantioselective Resolution against the Kazlauskas Rule To Afford γ-Amino Alcohols by Candida rugosa Lipase

Min, Bora; Park, Jeemin; Sim, Yong-Kyun; Jung, Suhyun; Kim, Seong-Ho; et al, ChemBioChem, 2015, 16(1), 77-82

合成路线：1 步

_92%

反应条件：

1.1 Solvents: Tetrahydrofuran , Water ; 2 h, 23 °C

参考文献：

Hexahydro-1H-Isoindolinone-Like Scaffolds from Electronically Deactivated and Sterically Hindered Dienes: Synthesis in the Context of Muironolide A

Olson, Christopher A.; Shaner, Courtnay E.; Roche, Sydney C.; Ferrence, Gregory M.; Mitchell, T. Andrew, Synthesis, 2015, 47(18), 2756-2766

合成路线：1 步

_91%

反应条件：

1.1 Solvents: Dichloromethane ; 18 h, 0 °C

参考文献：

Synthesis of substituted imidazolines by an Ugi/Staudinger/aza-Wittig sequence

Welsch, Sebastian J.; Umkehrer, Michael; Kalinski, Cedric; Ross, Guenther; Burdack, Christoph; et al, Tetrahedron Letters, 2015, 56(8), 1025-1029

合成路线：1 步

_91%

反应条件：

1.1 Solvents: Dichloromethane ; 15 min, 0 °C; 0 °C → rt; 18 h, rt

参考文献：

SnAP reagents for the synthesis of piperazines and morpholines

Luescher, Michael U.; Vo, Cam-Van T.; Bode, Jeffrey W., Organic Letters, 2014, 16(4), 1236-1239

合成路线：1 步

_87%

反应条件：

1.1 Reagents: Triethylamine Solvents: Dichloromethane ; 16 h, 20 °C

参考文献：

Polyfluorinated arylpyrazolopyrimidine compounds acting as Bruton's tyrosine kinase inhibitors and their preparation

, United States, , ,

合成路线：1 步

_87%