95-93-2 (1,2,4,5-四甲苯,1,2,4,5-Tetramethylbenzene)

反应条件：

1.1 Reagents: Water Catalysts: Trifluoromethanesulfonic acid Solvents: 1,2-Dichloroethane

参考文献：

The triflic acid-catalyzed deacylation and decarboxylation of polymethylbenzenecarbonyl derivatives under mild conditions

Keumi, Takashi; Morita, Toshio; Ozawa, Yoshihiro; Kitajima, Hidehiko, Bulletin of the Chemical Society of Japan, 1989, 62(2), 599-601

合成路线：1 步

1258975-24-4

344353-33-9

_84%

反应条件：

1.1 Catalysts: Palladium Solvents: Ethylene glycol ; 4 h, reflux

参考文献：

The use of Hagemann's esters to prepare highly functionalized phenols and benzenes

Majetich, George; Allen, Scott, ARKIVOC (Gainesville, 2010, (4), 104-124

合成路线：1 步

126696-88-6

_80%

反应条件：

1.1 Catalysts: Palladium

参考文献：

Cyclic dienes. XIII. Substituted 1,2-dimethylene-4-cyclohexenes

Bailey, Wm. J.; Rosenberg, Joseph; Young, Lewis J., Journal of the American Chemical Society, 1955, 77, 1163-6

合成路线：1 步

10340-77-9

_78%

反应条件：

1.1 Reagents: Triethylsilane , Aluminum chloride Solvents: Dichloromethane

参考文献：

Ionic and organometallic-catalyzed organosilane reductions

Larson, Gerald L.; Fry, James L., Organic Reactions (Hoboken, 2008, 71, 1-737

合成路线：1 步

13702-58-4

_68%

反应条件：

1.1 Catalysts: Silica Solvents: Toluene ; 12 h, 350 °C

参考文献：

Method for preparing benzene ring-containing compounds from pinacol

, China, , ,

合成路线：1 步

_65%

反应条件：

1.1 2.0 MPa, rt → 350 °C; 8 h, 180 °C

参考文献：

Method for preparing modified HZSM-5 molecular sieve catalyst for synthesizing tetramethylbenzene, and its prepared catalyst

, China, , ,

合成路线：1 步

_36%

反应条件：

1.1 Catalysts: Cupric nitrate ; 340 - 350 °C

参考文献：

Synthesis method of catalyst using grain size-adjustable small-grain ZSM-5 mol. sieve as carrier, and application thereof in preparation of durene from methanol and xylene

, China, , ,

合成路线：1 步

_35%

反应条件：

1.1 Catalysts: Zinc ; 330 - 340 °C

参考文献：

Method for preparing 1,2,4,5-tetramethylbenzene from methanol and xylene

, China, , ,

合成路线：1 步

_34%

反应条件：

1.1 4 MPa, 360 °C

参考文献：

Preparation of durene from methanol

, China, , ,

合成路线：1 步

_28%

反应条件：

1.1 2 s, 3 MPa, 390 °C
1.2 3 MPa, 380 °C

参考文献：

Device for preparing durene from methanol and C4 mixture, and application thereof in preparation of pyromellitic dianhydride and polyimide

, China, , ,

合成路线：1 步

108-88-3

_28%

反应条件：

1.1 3 s, 5 MPa, 390 °C

参考文献：

System and method for preparing 1,2,4,5-tetramethylbenzene with methylbenzene and methanol

, China, , ,

合成路线：1 步

2142-79-2

_10%

反应条件：

1.1 Reagents: Aluminum chloride

参考文献：

Transacylations between sterically hindered aromatic ketones and various arenes

El-Khawaga, Ahmed M.; Roberts, Royston M.; Sweeney, Kevin M., Journal of Organic Chemistry, 1985, 50(12), 2055-8

合成路线：1 步

反应条件：

1.1 Catalysts: Trifluoromethanesulfonic acid Solvents: 1-Ethyl-3-methylimidazolium tetrafluoroborate ; 0 °C; 4 h, 70 °C

参考文献：

Triflic acid-promoted transacylation and deacylation reactions in ionic liquid solvents

Sarca, Viorel D.; Laali, Kenneth K., Green Chemistry, 2004, 6(5), 245-248

合成路线：1 步

95-63-6

反应条件：

1.1 48 h, 3 MPa, 285 °C

参考文献：

Method and apparatus for alkylation of aromatics above C8

, China, , ,

合成路线：1 步

527-53-7

参考文献：

Purification of durene from the mixture of durene and isodurene by stripping crystallization

Shiau, Lie-Ding, Korean Journal of Chemical Engineering, 2021, 38(12), 2510-2518

合成路线：1 步

527-53-7

488-23-3

反应条件：

1.1 Reagents: Hydrogen ; 1.2 - 1.3 MPa, 200 - 230 °C; 1.0 - 1.2 MPa, 270 - 300 °C; 0.9 - 1.1 MPa, 110 - 130 °C

参考文献：

Apparatus and method for generating mesitylene from isodurene and prehnitene

, China, , ,

合成路线：1 步

630-08-0

反应条件：

1.1 2 MPa, 340 °C

参考文献：

Preparation of 1,2,4,5-tetramethylbenzene from carbon monoxide and methanol

, China, , ,

合成路线：1 步

95-63-6

反应条件：

1.1 0.1 MPa, 350 °C; 1.2 MPa, 380 °C

参考文献：

Green preparation of mesitylene by alkylation of aromatic hydrocarbons

, China, , ,

合成路线：1 步

115-10-6

反应条件：

1.1 1.5 MPa, 450 °C

参考文献：

Method for producing durene from xylene

, China, , ,

合成路线：1 步

108-88-3