98760-08-8 ((2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷,(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane)

快速询单

结构式：

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷MOL文件

CAS号：

98760-08-8

中文名称：

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷

英文名称：

(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane

分子式：

C₁₅H₂₁NO₃

分子量：

263.332144498825

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8)名称与标识符

名称

中文别名：

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷;(1S)-1-(2R)-环氧乙基-2-苯乙基氨基甲酸叔丁酯;[(1S)-1-(2R)-环氧乙烷-2-苯基乙基]-氨基甲酸-(1,1-二甲基)乙酯;(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷 (Boc Epoxy);(2R,3S)-1,2-环氧-3-Boc氨基-4-苯基丁烷;(2R,3S)-1,2-环氧-3-叔丁氧羰基;(2R,3S)-1,2-环氧基-3-(Boc-氨基)-4-苯基丁烷;(2R,3S)-3-(叔丁氧羰基)氨基-1,2-环氧-4-苯基丁烷;-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷;阿扎那韦杂质C;反式环氧化氨基苯丁酮;(1S,2R)-BOC环氧化物;阿扎那韦中间体;

英文别名：

tert-Butyl ((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate;(2r,3s)-3-(tert-butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane;(1S,2R)-Boc epoxide;(2R,3S)-N-BOC-3-amino-1,2-epoxy-4-phenylbutane;Boc Epoxy;Carbamic acid, (1-oxiranyl-2-phenylethyl)-, 1,1-dimethylethyl ester, [R-(R*,S*)]-;Carbamic acid, [(1S)-1-(2R)-oxiranyl-2-phenylethyl]-, 1,1-dimethylethyl ester (9CI (2R,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane;tert-Butyl [(1S)-1-[(2R)-oxiranyl]2-phenylethyl]carbamate;(2R,3S)-N-Boc-3-amino-1,2-epoxy-4-Phenylbutane (Boc Epoxy);(2R, 3S)-1,2-Epoxy-3-N-(tert-butoxycarbonyl)amino-4-phenylbutane;(2R,3S)-3-(N-BOC-AMINO)-1-OXIRANE-4-PHENYLBUTANE;(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane;(2R,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane;Carbamic acid, N-[(1S)-1-[(2R)-2-oxiranyl]-2-phenylethyl]-, 1,1-dimethylethyl ester;tert-butyl N-[(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate;Atozanavir Epoxide;(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane,Carbamic acid, N-[(1S)-1-(2R)-2-oxiranyl-2-phenylethyl]-, 1,1-dimethylethyl ester;(2R,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane;TERT-BUTYL[(1S,2R)-OXIRANYL-2-PHENYLETHYL]CARBAMATE;Carbamic acid, N-[(1S)-1-(2R)-2-oxiranyl-2-phenylethyl]-, 1,1-dimethylethyl ester;(2R,3S)-3-(t-BOC)amino-1,2-epoxy-4-phenylbutane;threo-N-Boc-L-phenylalanine epoxide;tert-butyl N-[(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl;NVPOUMXZERMIJK-STQMWFEESA-N;tert-Butyl(1S)-1-[(2R)-oxiran-2-y1]-2-phenylethylcarbamate;AC-132;Q-102797;(2R,3S)-3-(t-butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane;CS-B0126;tert-Butyl ((S)-(R ,R ))-(-)-(1-oxiranyl-2-phenylethyl)carbamate;AKOS015908505;N-tert-butoxycarbonyl-3(S)-amino-1,2(R)-epoxy-4-phenylbutane;2(R)-[1(S)-(Boc-amino)-2-phenylethyl]-oxirane;tert-Butyl[s-(r*,r*)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate;tert-butyl (s)-1-((r)-oxiran-2-yl)-2-phenylethylcarbamate;tert-Butyl[(1S)-1-(2R)-oxiranyl-2-phenylethyl]carbamate;tert-Butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate;AMY33463;DTXSID00431092;AC7588;(2R, 3S)-3-tert-butoxycarbonylamino-1,2-epoxy-4-phenylbutane;tert-butyl N-{(1S)-1-[(2R)oxiran-2-yl]-2-phenylethyl}carbamate;EN300-93022;98737-29-2;(2R,3s)-3-BOC-amino-1,2-epoxy-4-phenylbutane;t-butyl[(s)-1-((r)-oxiran-2-yl)-2-phenylethyl]carbamate;MFCD02258997;98760-08-8;Z1263823082;N-(tert-butoxycarbonyl)-2(S)-amino-1-phenyl-3(R)-3,4-epoxybutane;(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane;NS00077752;AS-15475;MFCD00671705;AC-206;tert-Butyl (1S)-1-[(2R)-oxiran-2-yl]-2-phenylethylcarbamate;SCHEMBL639229;tert-Butyl(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethylcarbamate;N-[(1S)-1-[(2R)-2-Oxiranyl]-2-phenylethyl]-carbamic Acid 1,1-Dimethylethyl Ester; (2R,3S)-(+)-3-tert-Butoxycarbonylamino-1,2-epoxy-4-phenylbutane; [(1S)-1-((2R)-Oxiranyl)-2-phenylethyl]carbamic Acid tert-Butyl Ester;;2-Methyl-2-propanyl {(1s)-1-[(2r)-2-oxiranyl]-2-phenylethyl}carbamate;DB-217461;431-870-3;DTXCID20381924;691-999-8;FB07938;tert-butyl ((1S)-1-((2R)-oxiran-2-yl)-2-phenylethyl)carbamate;

标识符

MDL：

MFCD00671705

InChIKey：

NVPOUMXZERMIJK-STQMWFEESA-N

Inchi：

1S/C15H21NO3/c1-15(2,3)19-14(17)16-12(13-10-18-13)9-11-7-5-4-6-8-11/h4-8,12-13H,9-10H2,1-3H3,(H,16,17)/t12-,13-/m0/s1

SMILES：

O1C[C@H]1[C@H](CC1C=CC=CC=1)NC(=O)OC(C)(C)C

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8)物化性质

实验特性

LogP : 2.91210
PSA : 50.86000
折射率 : 1.533
沸点 : 398.8℃ at 760 mmHg
熔点 : No data available
蒸气压 : 0.0±0.9 mmHg at 25°C
闪点 : 195.01℃
颜色与性状 : No data avaiable
密度 : 1.1±0.1 g/cm3

计算特性

精确分子量 : 263.15200
氢键供体数量 : 1
氢键受体数量 : 3
可旋转化学键数量 : 6
同位素质量 : 263.152
重原子数量 : 19
复杂度 : 305
同位素原子数量 : 0
确定原子立构中心数量 : 2
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 2.6
拓扑分子极性表面积 : 50.9

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8)安全信息

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8)海关数据

海关编码：

2924299090

海关数据：

中国海关编码：

2924299090

概述：

2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

申报要素：

品名, 成分含量, 用途, 包装

Summary：

2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8)推荐厂家更多厂家(79)

公司名称	手机号/电话	联系人	QQ	询单
江苏新素新材料有限公司	13914000513 0512-66387919	孙文婷	3771156959	询单
北京百灵威科技有限公司	18210857532	翟先生	3650742139	询单
湖北方德新材料有限公司	18086096695	邱经理	1462312301	询单
湖北扬信医药科技有限公司	18071854684 0714-3999001	程舒畅	2885409691	询单
湖北瑞诺医药科技有限公司	13165688766	汪经理	3008058303	询单
西安德而塔生物科技有限公司	18133906270 18133906270	张女士	2590956145	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364	询单
上海绩祥生物科技有限公司	18605105771	李经理	1799924424	询单
上海腾准生物科技有限公司	19821570922 021-34053661	张经理	3003871136	询单
南通众合化工新材料有限公司	18762756250 0513-55074056	胡经理	2369399482	询单

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8)上下游

地瑞那韦中间体 [(1S,2R)-1-苄基-2-羟基-3-[异丁基[(4-硝基苯基)磺酰]氨基]丙基]氨基甲酸叔丁酯 2-(2S,3S)-3-(叔丁氧基)羰基氨基-2-羟基-4-苯基丁基-2-4-(2-吡啶基)苯基甲基肼羧酸叔丁酯地瑞那韦乙醇盐

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8)相关文献

1. A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations
Sumit Kumar,Yash Gupta,Samantha E. Zak,Charu Upadhyay,Neha Sharma,Andrew S. Herbert,Ravi Durvasula,Vladimir Potemkin,John M. Dye,Poonam,Prakasha Kempaiah,Brijesh Rathi RSC Med. Chem. 2021 12 1757
2. A potent candidate against Zika virus infection: Synthesis, bioactivity, radiolabeling and biodistribution studies
Sumit Kumar,Neha Sharma,Willyenne Marilia Dantas,Jessica Catarine Frutuoso do Nascimento,Hannah Maus,Ronaldo Nascimento de Oliveira,Unnat Pandit,Agam P. Singh,Tanja Schirmeister,Puja Panwar Hazari,Lindomar Pena,Poonam,Brijesh Rathi New J. Chem. 2022 46 18764

(2R,3S)-1,2-环氧-3-叔丁氧羰基氨基-4-苯基丁烷(98760-08-8) MSDS

基础信息

Material Safety Data Sheet

Section 1. Identi?cation of the substance
Product Name: (2R,3S)-3-(t-BOC)amino-1,2-epoxy-4-phenylbutane
Synonyms: (2R,3S)-(+)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

Section 2. Hazards identi?cation
Harmful by inhalation, in contact with skin, and if swallowed.

Section 3. Composition/information on ingredients.
Ingredient name: (2R,3S)-3-(t-BOC)amino-1,2-epoxy-4-phenylbutane
CAS number: 98760-08-8

Section 4. First aid measures
    Skin contact:        Immediately wash skin with copious amounts of water for at least 15 minutes while removing
    contaminated clothing and shoes. If irritation persists, seek medical attention.
    Eye contact:        Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
    ?ushing of the eyes by separating the eyelids with ?ngers. If irritation persists, seek medical
    attention.
    Inhalation:        Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
    Ingestion:        Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section 5. Fire ?ghting measures
    In the event of a ?re involving this material, alone or in combination with other materials, use dry
    powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
    should be worn.

Section 6. Accidental release measures
    Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
    standards.
    Respiratory precaution:        Wear approved mask/respirator
    Hand precaution:        Wear suitable gloves/gauntlets
    Skin protection:        Wear suitable protective clothing
    Eye protection:        Wear suitable eye protection
    Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
    for disposal. See section 12.
    Environmental precautions: Do not allow material to enter drains or water courses.

Section 7. Handling and storage
    Handling:        This product should be handled only by, or under the close supervision of, those properly quali?ed
    in the handling and use of potentially hazardous chemicals, who should take into account the ?re,
    health and chemical hazard data given on this sheet.
    Store in closed vessels.
    Storage:

Section 8. Exposure Controls / Personal protection
    Engineering Controls: Use only in a chemical fume hood.
    Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
    General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section 9. Physical and chemical properties
    Appearance:        Not speci?ed
    Boiling point:        No data
    No data
    Melting point:
    Flash point:        No data
    Density:        No data
    Molecular formula:        C15H21NO3
    Molecular weight:        263.3

Section 10. Stability and reactivity
    Conditions to avoid: Heat, ?ames and sparks.
    Materials to avoid: Oxidizing agents.
    Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section 11. Toxicological information
No data.

Section 12. Ecological information
No data.

Section 13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section 14. Transportation information
Non-harzardous for air and ground transportation.

Section 15. Regulatory information
    No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
    302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
    Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A