IRAK4-IN-16

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IRAK4-IN-16

Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]-5-[(3R)-3-piperidinylamino]-

CAS No.： 1812188-83-2 分子式：C₁₇H₂₀F₂N₈O 分子量：390.39

简介

IRAK4-IN-16 (compound 4) 是一种有效的 IRAK4 (白细胞介素 -1 受体相关激酶 4) 抑制剂，IC50 为 2.5 nM。IRAK4-IN-16 对 OCI-LY10、TMD8、Ramos 和 HT 细胞表现出细胞毒性活性，其 IC50 分别为 0.2、0.2、0.6 和 2.7 μM。

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问答

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