SGC2085

中文名：SGC2085

英文名：SGC2085

纯度：Moligand™，≥99%

货号：S413977

Cas号：1821908-48-8

存储温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：

Information

SGC2085 SGC2085 is a potent and selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) inhibitor with an IC50 value of 50 nM and >100-fold selective over other PRMTs.

Targets

CARM1 (Cell-free assay) 50 nM

In vitro

With the exception of PRMT6 (IC50 = 5.2 μM), SGC2085 does not inhibit other PRMTs. Although CARM1(PRMT4) is previously shown to asymmetrically dimethylate BAF155 at R1064, no cellular activity is observed for SGC2085 when tested up to 10 μM. The absence of cellular activity for SGC2085 may due to poor permeability.

Cell Research(from reference)

Cell lines：HEK293 cells

Concentrations：up to 10 μM

Incubation Time：48 h

查看阿拉丁官网此产品相关对应页面：http://www.aladdin-e.com/zh_cn/S413977.html