4-Chloro-4-methyl-5-methylene-1,3-dioxolan-2-one (~90%)

Catalogue Number C371145 Chemical Name 4-Chloro-4-methyl-5-methylene-1,3-dioxolan-2-one (~90%) Synonyms Olmesartan Impurity; Number 95579-71-8 Molecular Formula C₅H₅ClO₃ Appearance Colourless to Yellow Oil Molecular Weight 148.54 Storage - 86°C, Hygroscopic, Light sensitive Solubility Chloroform (Sparingly), Ethyl Acetate (Slightly) Stability Moisture Sensitive Category Standards; Pharmaceutical/API Drug Impurities/Metabolites; Applications 4-Chloro-4-methyl-5-methylene-1,3-dioxolan-2-one is an impurity in the synthesis of Olmesartan (O550000), An angiotensin II receptor antagonist. Used as an anti-hypertensive. Olmesartan Medoxomil Impurity 4. References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996), Puchler, K., et al.: J. Hypertens., 15, 1809 (1997),