CAS:2172256-78-7|6-​Acetyl-​8-​cyclopentyl-​5-​methylpyrido[2,​3-​d]​pyrimidine-​2,​7(1H,​8H)​-​dione

产品编号：A173633
化学名称：6-​Acetyl-​8-​cyclopentyl-​5-​methylpyrido[2,​3-​d]​pyrimidine-​2,​7(1H,​8H)​-​dione
别名：Palbociclib Impurity;
Impurity:Palbociclib Impurity;
CAS号：2172256-78-7
分子式：C₁₅H₁₇N₃O₃
Appearance:Light Beige to Brown Solid
Melting Point:>201°C (dec.)
分子量：287.31
存储条件：-20°C, Inert atmosphere
溶解度：Chloroform (Slightly), Methanol (Slightly)
类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用：6-​Acetyl-​8-​cyclopentyl-​5-​methylpyrido[2,​3-​d]​pyrimidine-​2,​7(1H,​8H)​-​dione is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer.
参考文献：Finn, R., et al.: Breast Cancer Res., 11, 5 (2009);

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