产品编号：B503840
化学名称：(S)-tert-Butyl (2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate
别名：N-[2-[(2S)-2-Cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-1,1-dimethylethyl Ester Carbamic Acid
CAS号：1448440-50-3
分子式：C₁₂H₁₇F₂N₃O₃
分子量：289.28
类别：Research Tools; Molecular Biology; Amino Acids/Peptides;
应用：(S)-tert-Butyl (2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate is an intermediate in the synthesis of (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide (UAMC1110) (S687910) which is a useful research chemical and a fibroblast activation protein inhibitor displaying low nanomolar inhibitory potency and high selectivity against related dipeptidyl peptidases.
参考文献：De D., et al.: ACS Med. Chem., 10, 1173 (2019); Simon, P., et al.: ACS Chem. Biol., 13, 3333 (2018); De D., et al.: ACS Med. Chem. Lett., 10, 1173 (2019)
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