产品货号：A791720
产品名称：(3S,5R)-Atorvastatin Calcium Salt
Synonyms:(βS,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; USP Atorvastatin Related Compound B; Atorvastatin USP Related Compound B
Impurity:Atorvastatin USP Related Compound B
CAS号：887196-25-0
Alternate CAS #
Free Acid: 887324-52-9
分子式：C₆₆H₆₈CaF₂N₄O₁₀
Appearance:White to Pale Beige Solid
Melting Point:>235°C
分子量：1155.34
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用：(3S,5R)-Atorvastatin Calcium Salt (Atorvastatin USP Related Compound B) is an isomeric impurity of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
参考文献：Gupta, L. et al.: Spect. Acta. Mol. Biomol. Spect., 97, 495 (2012); Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),
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