产品货号：B592583
产品名称：1-(2,3-Epoxypropyl)-2-nitroimidazole
Synonyms:2-Nitro-1-(oxiranylmethyl)-1H-imidazole; 1-(2,3-Epoxypropyl)-2-nitro-imidazole; 2-Nitro-1-(2-oxiranylmethyl)-1H-imidazole; 1-(Oxiranylmethyl)-2-nitro-1H-imidazole;
CAS号：13551-90-1
分子式：C₆H₇N₃O₃
Appearance:White to Pale Yellow Solid
Melting Point:54 - 57ºC
分子量：169.14
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
应用：1-(2,3-Epoxypropyl)-2-nitroimidazole is an intermediate in the synthesis of Pimonidazole-d10 (P447814). Isotope labelled Pimonidazole (P447813) is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It abels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.
参考文献：Sato et al.: PLoS One 11 e0165946 PMID:(2016); Bennewith et al.: Cancer Res. 62 6827 PMID: 12460894, (2002)
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