产品货号：B674545
产品名称：3-Benzyl-6-bromo-2-chloroquinoline
Synonyms:6-Bromo-2-chloro-3-(phenylmethyl)quinoline
CAS号：654655-68-2
分子式：C₁₆H₁₁BrClN
分子量：332.62
Category:Building Blocks; Miscellaneous;
应用：3-Benzyl-6-bromo-2-chloroquinoline is an intermediate in the synthesis of (aS,bR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
参考文献：Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);
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