产品货号：B675700
产品名称：Bortezomib
Synonyms:B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid;
CAS号：179324-69-7
分子式：C₁₉H₂₅BN₄O₄
Appearance:White to Off-White Solid
Melting Point:>120°C (dec.)
分子量：384.24
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic, Light Sensitive, Moisture Sensitive
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用：Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献：Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);
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