产品货号：C246725
产品名称：Calebin A
同义名称：(E)-4-(4-Hydroxy-3-methoxyphenyl)-2-oxobut-3-en-1-y (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate;
CAS 号:336784-82-8
分子式：C₂₁H₂₀O₇
分子量：384.38
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites; Natural Products;
产品应用：Calebin A is a novel natural product of turmeric (Curcuma longa) rhizome that possess various pharmacological properties. Calebin A is a chemotherapeutic agent that suppresses cell growth, invasion and colony formation in colorectal cancer cells (CRC) by the suppression of NF-κB signaling. Calebin A potentiates the effect of 5-FU and TNF-beta (lymphotoxin alpha) against human colorectal cancer cells and potential role of NF-kappaB.
参考文献:Buhrmann, C., et al.: Int. J. Mol. Sci., 21, 2393 (2020); Majeed, A., et al.: J. Pure Appl. Microbiol., 13, 5636 (2019)
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