产品货号：D228735
产品名称：Defluoro-Canagliflozin
同义名称：(1S)-1,5-Anhydro-1-C-[4-methyl-3-[(5-phenyl-2-thienyl)methyl]phenyl]-D-glucitol, ,
CAS 号:842133-16-8
分子式：C₂₄H₂₆O₅S
分子量：426.53
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：Defluoro-Canagliflozin is an impurity of Canagliflozin (C175190), a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
参考文献:Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);
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