A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols†,10.1039/B612197G

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols†

Ian R. Baxendale,Steven V. Ley,Christopher D. Smith,Geoffrey K. Tranmer

Chemical Communications Pub Date : 10/03/2006 00:00:00 , DOI:10.1039/B612197G

Abstract

A general flow process for the multi-step assembly of peptides has been developed and this procedure has been used to successfully construct a series of Boc, Cbz and Fmoc N-protected dipeptides in excellent yields and purities, including an extension of the method to enable the preparation of a tripeptide derivative.