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A reusable, insoluble polymer-bound bis(oxazoline) (IPB-box) for highly enantioselective heterogeneous cyclopropanation reactions†
Alessandro Mandoli,Simonetta Orlandi,Dario Pini,Piero Salvadori
Chemical Communications Pub Date : 09/04/2003 00:00:00 , DOI:10.1039/B306483B
Abstract

A reusable, insoluble polystyrene-supported bis(oxazoline) was developed, affording e.e.s >90% in the heterogeneous enantioselective cyclopropanation of styrene and 1,1-disubstituted alkenes with ethyl diazoacetate.

Graphical abstract: A reusable, insoluble polymer-bound bis(oxazoline) (IPB-box) for highly enantioselective heterogeneous cyclopropanation reactions
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