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Pharmaceutically active ionic liquids with solids handling, enhanced thermal stability, and fast release†‡
Katharina Bica,Héctor Rodríguez,Gabriela Gurau,O. Andreea Cojocaru,Anders Riisager,Rasmus Fehrmann,Robin D. Rogers
Chemical Communications Pub Date : 03/28/2012 00:00:00 , DOI:10.1039/C2CC30959A
Abstract

Pharmaceutically active compounds in ionic liquid form immobilized onto mesoporous silica are stable, easily handled solids, with fast and complete release from the carrier material when placed into an aqueous environment. Depending on specific ion-surface interactions, they may also exhibit improved thermal stability when compared to the non-adsorbed compounds.

Graphical abstract: Pharmaceutically active ionic liquids with solids handling, enhanced thermal stability, and fast release
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