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Protective group-free synthesis of new chiral diaminesvia direct azidation of 1,1-diaryl-2-aminoethanols†
Harendra Nath Roy,Arigala Pitchaiah,Miri Kim,In Taek Hwang
RSC Advances Pub Date : 01/23/2013 00:00:00 , DOI:10.1039/C3RA23205K
Abstract

A direct azidation of tertiary alcohols using sodium azidesulfuric acid is described; the present method provides an efficient and practical path for the synthesis of new chiral diamines from unmasked 1,1-diaryl-2-aminoethanols derived from natural amino acids.

Graphical abstract: Protective group-free synthesis of new chiral diamines via direct azidation of 1,1-diaryl-2-aminoethanols
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