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Rh(i)-Catalyzed regioselective arylcarboxylation of acrylamides with arylboronic acids and CO2†
Lei Fu,Yuzhen Gao,Shangda Li
Green Chemistry Pub Date : 09/24/2020 00:00:00 , DOI:10.1039/D0GC02667K
Abstract

The first Rh(I)-catalyzed regioselective arylcarboxylation of electron-deficient acrylamides with arylboronic acids under atmospheric pressure of CO2 has been developed. A range of acrylamides and arylboronic acids were compatible with this reaction under redox-neutral conditions, leading to a series of malonate derivatives that are versatile building blocks in organic syntheses.

Graphical abstract: Rh(i)-Catalyzed regioselective arylcarboxylation of acrylamides with arylboronic acids and CO2
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