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Spontaneous vesiculation: a mechanistic insight from the study of hybrid peptide molecules†
Appa Rao Sapala,Jayanta Kundu,Pramit Chowdhury,V. Haridas
New Journal of Chemistry Pub Date : 11/04/2016 00:00:00 , DOI:10.1039/C6NJ02643E
Abstract

We report a series of simple acyclic molecules that display spontaneous vesiculation. A closer look at their vesicle formation revealed a toroidal intermediate en route to the final vesicular form. Electron and optical microscopy based imaging along with dye encapsulation using commonly used fluorescent reporters help reveal the inner dynamics of the morphogenesis.

Graphical abstract: Spontaneous vesiculation: a mechanistic insight from the study of hybrid peptide molecules
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