960化工网
Synthesis of (1R,2R)-DPEN-derived triazolium salts and their application in asymmetric intramolecular Stetter reactions†
Min-Qiang Jia,Yi Li,Zi-Qiang Rong,Shu-Li You
Organic & Biomolecular Chemistry Pub Date : 02/02/2011 00:00:00 , DOI:10.1039/C1OB00025J
Abstract

A series of novel chiral triazolium salts has been synthesized from readily available (1R,2R)-DPEN and found to be efficient for the enantioselective intramolecular Stetter reaction. With 10 mol% of the catalyst, the intramolecular Stetter reaction was realized in excellent yields with up to 97% ee.

Graphical abstract: Synthesis of (1R,2R)-DPEN-derived triazolium salts and their application in asymmetric intramolecular Stetter reactions
平台客服
平台客服
平台在线客服