Ensemble hybridisation – a new method for exploring sequence dependent fluorescence of dye–nucleic acid conjugates
Olaf Köhler,Dilip Venkatrao Jarikote,Oliver Seitz
Chemical Communications Pub Date : 10/14/2004 00:00:00 , DOI:10.1039/B411877D
Abstract
The fluorescence of thiazole orange as artificial base in PNA was investigated in a nearest neighbour analysis; library-to-library hybridisation allowed the identification of probe sequences suitable for homogeneous DNA detection.
