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Metal–ligand bifunctional activation and transfer of N–H bonds†
Anton Lishchynskyi,Jan Streuff,Martin Nieger,Eduardo C. Escudero-Adán,Marta Martínez Belmonte
Chemical Communications Pub Date : 03/24/2011 00:00:00 , DOI:10.1039/C1CC10999E
Abstract

The concept of metal–ligand bifunctionality can be employed for an efficient activation of N–H bonds by well-defined ruthenium amido complexes. An enantioselective catalytic aza-Michael reaction was developed on the basis of this process, which gives rise to indoline β-amino acids.

Graphical abstract: Metal–ligand bifunctional activation and transfer of N–H bonds
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