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One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment†
Robert. C. Martin,Erica Locatelli,Yan Li,Paolo Matteini,Ilaria Monaco,Guozhen Cui,Suping Li,Martina Banchelli,Roberto Pini,Mauro Comes Franchini
Journal of Materials Chemistry B Pub Date : 12/09/2015 00:00:00 , DOI:10.1039/C5TB02499D
Abstract

A novel highly biocompatible nanosystem made up of a chitosan matrix and filled with magnesium nanoparticles was synthesized using a simple and one-pot strategy, and tested as a promising, well-tolerated tool for photothermal therapy. Moreover, in vivo a proof of concept on hepatocarcinoma-bearing mice is presented.

Graphical abstract: One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment
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