Traceless solid phase synthesis of natural product inspired cis-1,2-dehydrodecalins†
Masahito Yoshida,Christian Hedberg,Markus Kaiser
Chemical Communications Pub Date : 04/01/2009 00:00:00 , DOI:10.1039/B901041F
Abstract

A tetrazole-based traceless linker for Diels–Alder reactions on solid support which can be cleaved by Pd(0)-, Cu(I)- and Ag(I)-assisted nucleophilic displacements has been developed and applied to the solid-phase/traceless release synthesis of natural product inspired cis-decalins.

Graphical abstract: Traceless solid phase synthesis of natural product inspired cis-1,2-dehydrodecalins