Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N†
Xin Wang,Elena Matei,Lingquan Deng,Olof Ramström,Angela M. Gronenborn,Mingdi Yan
Chemical Communications Pub Date : 06/30/2011 00:00:00 , DOI:10.1039/C1CC12981C
Abstract
Low-mannose (LM) structures were coupled to gold nanoparticles (Au NPs) to amplify the affinity of LMs with Cyanovirin-N (CV-N) lectins and to study the structures of CV-N variants CVNQ50C and CVNMutDB.