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Base-promoted [1,4]-Wittig rearrangement of chalcone-derived allylic ethers leading to aromatic β-benzyl ketones†
Fei Ye,Xiao-Yun Dong,Yun Chen,Zi-Wei Gao,Wei-Qiang Zhang
RSC Advances Pub Date : 04/07/2015 00:00:00 , DOI:10.1039/C5RA03846D
Abstract

n-BuLi-promoted [1,4]-Wittig rearrangement of allylic ethers was developed successfully in this work, in which the Wittig rearrangement reaction provided a facile approach to the synthesis of aromatic β-benzyl ketones under mild reaction conditions.

Graphical abstract: Base-promoted [1,4]-Wittig rearrangement of chalcone-derived allylic ethers leading to aromatic β-benzyl ketones
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