Double-sided Tl2Ba2CaCu2O8 (Tl-2212) films for device applications have been fabricated through thallium vapor diffusion into BaCaCuOF matrices deposited by a novel metal-organic chemical vapor deposition (MOCVD) process onto 10 × 10 mm2 LaAlO3 (100) substrates. The present approach uses a multimetal molten single source in a monocomponent hot-wall MOCVD reactor whose geometry allows simultaneous and uniform film growth on both sides of the substrate. Both sides are epitaxially coated by homogeneous and monophasic Tl-2212 films, which, even more importantly, have comparable superconducting and transport properties.