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Aryne reaction with trifluoromethylketones in three modes: C–C bond cleavage, [2+2] cycloaddition and O-arylation†
Hiroto Yoshida,Yu Ito,Yunito Yoshikawa,Joji Ohshita,Ken Takaki
Chemical Communications Pub Date : 06/27/2011 00:00:00 , DOI:10.1039/C1CC12820E
Abstract

Trifluoromethyl ketones were found to be coupled with arynes in three modes depending upon their substitution patterns, namely C–C bond cleavage, [2+2] cycloaddition and O-arylation.

Graphical abstract: Aryne reaction with trifluoromethyl ketones in three modes: C–C bond cleavage, [2+2] cycloaddition and O-arylation
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