A novel nano-Fe3O4–MoO3 (Nanocat-Fe–Mo) catalyst was prepared via simple wet impregnation and characterized by several techniques. The synthesized Nanocat-Fe–Mo was found to be a highly active and efficient catalyst in the oxidation of benzyl alcohol and a series of examples of important organic reactions including A3 couplings, hydrogenations and hydrations. The Nanocat-Fe–Mo could be reused and recycled up to 7 times without any significant yield loss.