2. Metabolic Enzyme/Protease Anti-infection
  3. Herbicide Fungal Mitochondrial Metabolism
  4. 2,6-Dichloro-4-nitroaniline

2,6-Dichloro-4-nitroaniline 是一种具有口服活性的除草剂 (Herbicide)、杀真菌剂 (Fungicide) 和解偶联剂。2,6-Dichloro-4-nitroaniline 可解偶联氧化磷酸化并抑制电子传递。2,6-Dichloro-4-nitroaniline 可诱导大鼠肝脏中联苯羟化酶活性。2,6-Dichloro-4-nitroaniline 可通过肝脏肿大提高大鼠肝脏相对重量，但不改变其体重。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

2,6-Dichloro-4-nitroaniline

2,6-Dichloro-4-nitroaniline Chemical Structure

CAS No. : 99-30-9

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
25 g ￥100
In-stock
50 g ￥140
In-stock
100 g ￥200
In-stock
500 g ￥360
In-stock
1 kg ￥560
In-stock

* Please select Quantity before adding items.

2,6-Dichloro-4-nitroaniline 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2,6-Dichloro-4-nitroaniline is an orally active Herbicide, Fungicide and uncoupler. 2,6-Dichloro-4-nitroaniline uncouples oxidative phosphorylation and inhibits electron transport. 2,6-Dichloro-4-nitroaniline induces biphenyl hydroxylase activity in rat liver. 2,6-Dichloro-4-nitroaniline increases the relative liver weight of rats via hepatomegaly without altering their body weight[1].

体外研究
(In Vitro)

2,6-Dichloro-4-nitroaniline (1×10-5-1×10-4 M) 可解偶联离体肝线粒体的氧化磷酸化并抑制其电子传递[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2,6-Dichloro-4-nitroaniline 相关抗体:
体内研究
(In Vivo)

2,6-Dichloro-4-nitroaniline (500-1000 mg/kg；口服；单次；连续 4 天；连续最长 12 周) 可诱导雌性 Sprague-Dawley 大鼠的肝脏肿大和联苯羟化酶活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley (female, 100-150 g)[1]
Dosage: 500-1000 mg/kg; 1000 mg/kg (single dose); 1000 mg/kg (daily for 4 days); 500 mg/kg (daily for up to 12 weeks)
Administration: p.o.; single dose; daily (4 consecutive days); daily (up to 12 weeks)
Result: Increased hepatic mitochondrial respiratory rate by 18% (16 hours post single 1000 mg/kg dose, succinate as substrate).
Did not alter ADP/O ratio at 1, 16, or 24 hours post single 1000 mg/kg dose.
Increased hepatic 4-OH biphenyl hydroxylase activity to 2.545 μmol/hr/g fresh liver and 2-OH biphenyl hydroxylase activity to 0.513 μmol/hr/g fresh liver (24 hours post single 1000 mg/kg dose).
Increased hepatic mitochondrial respiratory rate to 54.15, 50.94, and 44.53 nmol O2/min/mg protein (1000 mg/kg daily for 2, 3, 4 days respectively, succinate as substrate).
Did not alter ADP/O ratio (1000 mg/kg daily for 2, 3, 4 days).
Increased relative liver weight to 7.10, 7.43, and 6.10 (1000 mg/kg daily for 2, 3, 4 days respectively).
Increased hepatic 4-OH biphenyl hydroxylase activity to 3.705, 5.205, and 4.275 μmol/hr/g fresh liver and 2-OH biphenyl hydroxylase activity to 3.715, 5.181, and 4.385 μmol/hr/g fresh liver (1000 mg/kg daily for 2, 3, 4 days respectively).
Increased relative liver weight to 6.7, 8.1, 6.1, and 5.6 (500 mg/kg daily for 2, 4, 8, 12 weeks respectively).
Increased hepatic 4-OH biphenyl hydroxylase activity to 1.710, 2.27, 1.16, and 3.46 μmol/hr/g fresh liver and 2-OH biphenyl hydroxylase activity to 2.378, 1.48, 1.05, and 4.45 μmol/hr/g fresh liver (500 mg/kg daily for 2, 4, 8, 12 weeks respectively).
Elevated respiratory activity in 33,000 g·min heavy mitochondrial pellet throughout 3 months of 500 mg/kg daily treatment.
Detected ~1×10-5 M DCNA in whole liver homogenate and crude nuclear pellet (500 mg/kg daily for 4 days).
Detected 37.2 μg/mL DCNA in urine (single 1000 mg/kg dose) and 30.6 μg/mL DCNA in urine (500 mg/kg daily for 30 days).
分子量

207.01

Formula

C6H4Cl2N2O2
CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

2,6-Dichloro-4-nitroaniline 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,6-Dichloro-4-nitroaniline99-30-9HerbicideFungalMitochondrial Metabolismdrug-processing enzymeselectron transportratshepatic lysosomesmooth endoplasmic reticulummicrosomal hydroxylationoxidative phosphorylationhepatic mitochondriarespiratory enzymesbiphenyl hydroxylaseInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
2,6-Dichloro-4-nitroaniline
目录号：
HY-W040305
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z