1. Anti-infection Metabolic Enzyme/Protease
  2. Bacterial Endogenous Metabolite Parasite
  3. Ambigol C

Ambigol C 是一种 Ambigol、抗菌 (Antibacterial) 剂和抗疟 (Antimalarial) 剂。Ambigol C 可从 Fischerella ambigua 108b 分离。 Ambigol C 对革兰氏阳性金黄色葡萄球菌菌株 (包括 MRSA) 表现出选择性抗菌活性,MIC 值为 0.98-3.91 μg/mL。Ambigol C 对 B. megaterium 也表现出较强的抗菌活性,并具有微弱的抗疟原虫和杀锥虫作用。Ambigol C 可用于细菌感染、疟原虫感染、锥虫感染的研究。

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Ambigol C

Ambigol C Chemical Structure

CAS No. : 850655-31-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ambigol C is an ambigol, Antibacterial agent and Antimalarial agent. Ambigol C is isolated from Fischerella ambigua 108b. Ambigol C exhibits selective antibacterial activity against Gram-positive Staphylococcus aureus strains (including MRSA) with MIC values of 0.98-3.91 μg/mL. Ambigol C also shows potent antibacterial activity against B. megaterium, and possesses weak antimalarial and trypanocidal effects. Ambigol C can be used in the research of bacterial infections, plasmodial infections and trypanosomal infections[1].

IC50 & Target[1]

Microbial Metabolite

 

Trypanosoma

 

Plasmodium

 

体外研究
(In Vitro)

Ambigol C (抗菌/抗真菌作用 24 h,细胞毒性作用 48 h) 对革兰氏阳性金黄色葡萄球菌菌株 (包括 MRSA) 表现出选择性抗菌活性,MIC 值为 0.98-3.91 μg/mL,对大肠杆菌或白色念珠菌无活性,对肺成纤维细胞 MRC-5 的 IC50 为 40 μg/mL[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

484.97

Formula

C18H8Cl6O3

CAS 号
结构分类
初始来源

Fischerella ambigua

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Ambigol C
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HY-N18878
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