2. Anti-infection Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Bacterial Reactive Oxygen Species (ROS)
  4. Antibacterial agent 326

Antibacterial agent 326 是一种杀菌剂，可抑制多种细菌 (bacterial) 的生长。Antibacterial agent 326 可抑制大肠杆菌的生物膜形成，破坏细菌细胞膜，诱导大肠杆菌产生氧化应激和脂质过氧化，升高 ROS 水平，降低 GSH 活性。Antibacterial agent 326 可用于细菌感染 (包括大肠杆菌、金黄色葡萄球菌、粪肠球菌、李斯特菌属、枯草芽孢杆菌、粘质沙雷氏菌、肠炎沙门氏菌、乙酸钙不动杆菌引起的感染) 的研究。

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Antibacterial agent 326

Antibacterial agent 326 Chemical Structure

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Antibacterial agent 326 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 326 is a bactericide that inhibits the growth of various bacterial strains. Antibacterial agent 326 inhibits biofilm formation in Escherichia coli, disrupts bacterial cell membranes, induces oxidative stress and lipid peroxidation in Escherichia coli, increases ROS levels, and reduces GSH activity. Antibacterial agent 326 can be used in studies of bacterial infections, including those caused by Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, Listeria spp., Bacillus subtilis, Serratia marcescens, Salmonella enteritidis and Acinetobacter calcoaceticus[1].

体外研究
(In Vitro)

Antibacterial agent 326 (Compound 12) (1.56-3.12 μg/mL) 可抑制 S. aureus，E. faecalis，L. species，B. subtilis，S. marcescens，E. coli，S. enterica，A. calcoaceticu 的生长，MIC 分别为1.56，1.56，3.12，1.56，3.23，1.56，3.12，1.56 μg/mL[1]。
Antibacterial agent 326 在琼脂纸片扩散法实验中对 Escherichia coli 产生 22.7 mm 的抑菌圈，显示出较强的抗菌活性[1]。
Antibacterial agent 326 (0-12.5 μg/mL; up to 660 min) 对大肠杆菌表现出快速的、浓度依赖性杀菌活性，抑制大肠杆菌生物膜的形成，提高大肠杆菌的内膜通透性，破坏大肠杆菌的膜完整性，去极化大肠杆菌 的细胞膜[1]。
Antibacterial agent 326 (1.56-12.5 μg/mL) 可在大肠杆菌中引发浓度依赖性代谢功能异常，诱导大肠杆菌产生细胞内氧化应激，升高 ROS 水平，破坏大肠杆菌的细胞抗氧化防御系统，降低 GSH 活性[1]。
Antibacterial agent 326 (12.5 μg/mL) 可在大肠杆菌中诱导脂质过氧化，提升 MDA 生成量[1]。
Antibacterial agent 326 会破坏 大肠杆菌的细胞形态，导致其表面出现褶皱、收缩、塌陷和碎裂[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 326 相关抗体:

Immunofluorescence[1]

Cell Line: Escherichia coli
Concentration: 1.56 μg/mL
Incubation Time: 30 min)
Result: Exhibited red fluorescence (PI), confirming membrane disintegration.
分子量

489.39

Formula

C24H17BrN4OS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 326 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 326Antibacterial agent326Antibacterial agent-326BacterialReactive Oxygen Species (ROS)bactericideEscherichia coliStaphylococcus aureusEnterococcus faecalisListeria spp.Bacillus subtilisSerratia marcescensSalmonella enteritidisAcinetobacter calcoaceticusInhibitorinhibitorinhibit

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