2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 329

Antibacterial agent 329 (Compound 9c) 是一种抗菌 (antibacterial) 剂。Antibacterial agent 329 抑制 MraY 的活性。Antibacterial agent 329 对 Escherichia coli K12 和 Bacillus subtilis W23 具有抗菌活性，MIC 为 16 μg/mL，而对 Pseudomonas fluorescens Pf-5 无活性。Antibacterial agent 329 对鲍曼不动杆菌 19606、金黄色葡萄球菌 MRSA USA300 JE2、阴沟肠杆菌 19434、肺炎克雷伯菌 700603 和屎肠球菌 19434 表现出抗菌活性，其 MIC 值分别为 8、8、16-32、16-32 和 16 μg/mL，而对铜绿假单胞菌 NCTC 13437 无活性。

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Antibacterial agent 329

Antibacterial agent 329 Chemical Structure

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Antibacterial agent 329 相关抗体

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  • 生物活性

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生物活性

Antibacterial agent 329 (Compound 9c) is an antibacterial agent. Antibacterial agent 329 inhibits the activity of MraY. Antibacterial agent 329 exhibits antibacterial activity against Escherichia coli K12 and Bacillus subtilis W23 with a MIC of 16 μg/mL, but shows no activity against Pseudomonas fluorescens Pf-5. Antibacterial agent 329 exerts antibacterial activity against Acinetobacter baumannii 19606, Staphylococcus aureus MRSA USA300 JE2, Enterobacter cloacae 19434, Klebsiella pneumoniae 700603 and Enterococcus faecium 19434, with MIC values of 8, 8, 16-32, 16-32 and 16 μg/mL, respectively, while it shows no activity against Pseudomonas aeruginosa NCTC 13437[1].

体外研究
(In Vitro)

Antibacterial agent 329 对 Escherichia coli K12 和 Bacillus subtilis W23 具有抗菌活性，MIC 为 16 μg/mL，而对 Pseudomonas fluorescens Pf-5 无活性[1]。
Antibacterial agent 329 对鲍曼不动杆菌 19606、金黄色葡萄球菌 MRSA USA300 JE2、阴沟肠杆菌 19434、肺炎克雷伯菌 700603 和 屎肠球菌 19434 表现出抗菌活性，其 MIC 值分别为 8、8、16-32、16-32 和 16 μg/mL，而对铜绿假单胞菌 NCTC 13437 无活性[1]。
Antibacterial agent 329 (200 μM) 将大肠杆菌颗粒型 MraY 的活性抑制 33%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 329 相关抗体:
分子量

333.31

Formula

C17H14F3N3O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 329 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 329Antibacterial agent329Antibacterial agent-329BacterialBacillus subtilis W23Escherichia coli translocase MraYpeptidoglycan biosynthesis pathwayEscherichia coli K12Staphylococcus aureus MRSA USA300acinetobacter baumannii infectionstaphylococcus aureus mrsa infectionAcinetobacter baumannii 19606HepG2 cellsPseudomonas fluorescens Pf-5Inhibitorinhibitorinhibit

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