1. Anti-infection
  2. Bacterial
  3. Antibiofilm agent-18

Antibiofilm agent-18 是一种四氢吡啶衍生物,具有抑制生物膜形成的作用。Antibiofilm agent-18 能够破坏金黄色葡萄球菌 (S. aureus) 和铜绿假单胞菌 (P. aeruginosa) 的生物膜,且具有较低的细胞毒性。抗菌生物膜剂-18 可用于细菌感染相关研究。

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Antibiofilm agent-18

Antibiofilm agent-18 Chemical Structure

CAS No. : 1989688-84-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibiofilm agent-18, a tetrahydropyrid derivative is a biofilm inhibitor. Antibiofilm agent-18 can disrupts S. aureus and P. aeruginosa biofilms and has low cytotoxicity. Antibiofilm agent-18 can be used for the research of bacterial infection[1].

体外研究
(In Vitro)

Antibiofilm agent-18 (5-15 μg/mL;24 h) (Compound 4I) 以剂量依赖方式破坏金黄色葡萄球菌 (S. aureus) 和铜绿假单胞菌 (P. aeruginosa) 生物膜[1]
Antibiofilm agent-18 (100 μg/mL;24-48 h) 在 AGS 细胞中表现出低细胞毒性[1]
Antibiofilm agent-18 能与多种生物膜相关蛋白 (sarA、crtM、fnbA、PBP2、clfA、clfB、AgrA 和 Agrc) 高亲和力结合[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

571.54

Formula

C34H32Cl2N2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antibiofilm agent-18
目录号:
HY-180998
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