2. Anti-infection
  3. Bacterial
  4. Antitubercular agent-54

Antitubercular agent-54 是一种抗结核剂，具有强大的巨噬细胞内活性 (EC50 值为 0.68 μM)。Antitubercular agent-54 对胆固醇培养的的结核分枝杆菌 (Mycobacterium tuberculosis，Mtb) H37Rv 的 MIC 值为 0.31 μM。Antitubercular agent-54 可用于结核病的研究。

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Antitubercular agent-54

Antitubercular agent-54 Chemical Structure

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Antitubercular agent-54 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitubercular agent-54 is an antitubercular agent with potent intramacrophage activity (EC50 = 0.68 μM). Antitubercular agent-54 shows a MIC of 0.31 μM against Mycobacterium tuberculosis (Mtb) H37Rv in cholesterol-containing medium. Antitubercular agent-54 can be used for the research of tuberculosis[1].

体外研究
(In Vitro)

Antitubercular agent-54 (Compound P39) 对不同代谢状态的 Mtb 均具有强效抑制活性，对巨噬细胞内 Mtb 的 EC50 为 0.68 μM，在胆固醇培养基中对 Mtb H37Rv 的 MIC 为 0.31 μM[1]。
Antitubercular agent-54 (>40 μM) 对 HEK293T 和 HepG2 细胞无明显细胞毒性，安全性良好[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antitubercular agent-54 相关抗体:
分子量

301.34

Formula

C15H19N5O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitubercular agent-54 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitubercular agent-54Antitubercular agent54Antitubercular agent 54BacterialHEK293THepG2Inhibitorinhibitorinhibit

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