2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. AVID100 Antibody

AVID100 Antibody  (Synonyms: MAB100 Antibody)

目录号: HY-P991967
一键复制产品信息
技术支持

AVID100 Antibody (MAB100) 是一种靶向 EGFR 的单克隆抗体抑制剂，可用于合成一种新型的抗体药物偶联物 (ADC) 分子 AVID100。AVID100 Antibody 可用于乳腺癌、头颈癌、肺癌的相关研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

AVID100 Antibody

AVID100 Antibody Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
1 mg   询价  
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

AVID100 Antibody 相关抗体

Top Publications Citing Use of Products

查看 EGFR 亚型特异性产品:

查看所有亚型
EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AVID100 Antibody (MAB100) is a monoclonal antibody inhibitor targeting EGFR, which can be used to synthesize a novel antibody-drug conjugate (ADC) molecule AVID100. AVID100 Antibody is applicable to relevant research on breast cancer, head and neck cancer, and lung cancer[1].

反应种属

Human
体外研究
(In Vitro)

AVID100 Antibody (MAB100) 以约 2 nM 的亲和力结合 EGFR，是一种完全 EGFR 拮抗剂，可阻断下游信号传导，并与 EGF 竞争结合 EGFR[1]。
AVID100 可在 MDA-MB-468、H292 和 FaDu 癌细胞中诱导细胞凋亡并产生强细胞毒性 (其 IC50 values correlating with EGFR expression)，但相较于未偶联的 MAB100，不会增强正常角质形成细胞的细胞毒性或细胞凋亡水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AVID100 Antibody 相关抗体:
基因 ID

1956  [NCBI]

Accession
靶点

ERBB1/EGFR/HER1
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AVID100 Antibody 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AVID100 AntibodyMAB100 AntibodyEGFREpidermal growth factor receptorErbB-1HER1normal keratinocytesbreast cancerlung cancerEGFDM1mouse xenograft modelscynomolgus monkeyshead and neck cancerapoptosisInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
AVID100 Antibody
目录号：
HY-P991967
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z