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  2. Bacterial
  3. BDM31343

BDM31343 是一种 Ethionamide (HY-B0276) 的增效剂。BDM31343 通过抑制结核分枝杆菌中的转录抑制因子 EthR,解除 Ethionamide 激活酶 EthA 的抑制,从而增强 Ethionamide 的疗效。BDM31343 有效抑制 EthR 与 DNA 的结合,其 IC₅₀ 为 3.3 μM。BDM31343 可用于抗结核分枝杆菌研究。

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BDM31343

BDM31343 Chemical Structure

CAS No. : 1001468-07-0

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生物活性

BDM31343 is an Ethionamide (HY-B0276) synergist. BDM31343 inhibits the transcriptional repressor EthR in Mycobacterium tuberculosis, thereby relieving the inhibition of the EthA activator by Ethionamide, and enhancing the efficacy of Ethionamide. BDM31343 effectively inhibits the binding of EthR to DNA, with its IC₅₀ being 3.3 μM. BDM31343 can be used in the research of anti-Mycobacterium tuberculosis[1][2].

分子量

302.35

Formula

C14H14N4O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
BDM31343
目录号:
HY-165540
需求量: