2. Anti-infection Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Bacterial Apoptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism
  4. Dichamanetin

Dichamanetin 是一种 C- 苄基化黄烷酮，可从胡椒属植物 (Piper sarmentosum) 中分离得到，具有强效的抗菌和抗癌活性。Dichamanetin 对多种革兰氏阳性菌菌株均表现出抗菌活性，包括耐药的金黄色葡萄球菌菌株，其 MIC 值在 1-7.5 μg/mL 范围内。Dichamanetin 通过线粒体 (mitochondrial) 介导的细胞凋亡 (apoptosis)，影响活性氧 (ROS 相关的信号通路，从而抑制癌细胞生长。Dichamanetin 可用于结肠癌、前列腺癌、乳腺癌和感染的研究。

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Dichamanetin

Dichamanetin Chemical Structure

CAS No. : 58779-09-2

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Dichamanetin 相关抗体

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  • 生物活性

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生物活性

Dichamanetin, a C-benzylated flavanone that can be isolated from Piper sarmentosum, is a potent antibacterial and anticancer agent. Dichamanetin displays antibacterial activity against a panel of Gram-positive strains, including resistant S. aureus strains with MIC values in the range of 1-7.5 μg/mL. Dichamanetin inhibits cancer cell growth by affecting ROS-related signaling components via mitochondrial-mediated apoptosis. Dichamanetin can be used for colon, prostate, breast cancer and infection research[1][2].

分子量

468.50

Formula

C29H24O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dichamanetin 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dichamanetin58779-09-2BacterialApoptosisReactive Oxygen Species (ROS)Mitochondrial MetabolismHT-29colonDU145prostateMDA-MB-231breast cancerInhibitorinhibitorinhibit

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