1. 天然产物
  2. 植物 萜类
  3. 商陆科 五环三萜
  4. 垂序商陆
  5. Esculentoside L

Esculentoside L 是一种存在于美洲商陆 (Phytolacca americana) 根中的三萜皂苷。Esculentoside L 可增加多药耐药性人卵巢癌细胞中钙黄绿素的细胞内积累量。Esculentoside L 对非癌细胞和肝细胞无显著细胞毒活性。Esculentoside L 可用于多药耐药性人卵巢癌的相关研究。

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Esculentoside L

Esculentoside L Chemical Structure

CAS No. : 130364-33-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Esculentoside L is a triterpene saponin present in the roots of Phytolacca americana. Esculentoside L increases the intracellular accumulation of calcein in multidrug-resistant human ovarian cancer cells. Esculentoside L exerts no significant cytotoxic activity against non-cancerous cells and hepatocytes. Esculentoside L can be used in studies related to multidrug-resistant human ovarian cancer[1].

体外研究
(In Vitro)

Esculentoside L (0.25-25 μg/mL) 可增加多药耐药性人卵巢癌细胞 2780AD 中的钙黄绿素积累[1]
Esculentoside L 对 WI-38、VA-13、HepG2 和 A549 细胞无显著细胞毒性,其 IC50 值均大于 103 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

973.11

Formula

C48H76O20

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Esculentoside L
目录号:
HY-N18168
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