1. Anti-infection Metabolic Enzyme/Protease Immunology/Inflammation NF-κB Cell Cycle/DNA Damage Apoptosis
  2. Fungal Reactive Oxygen Species (ROS) DNA/RNA Synthesis Apoptosis
  3. Fluoxastrobin

Fluoxastrobin 是一种抗真菌剂。Fluoxastrobin 通过结合 NAD 依赖性表异构酶/脱水酶,干扰电子传递、减少 ATP 产生并抑制菌丝生长,从而有效控制茶树叶部病害。Fluoxastrobin 可通过提高 ROS 水平和脂质过氧化作用诱导氧化应激,造成 DNA 损伤,促进细胞凋亡 (apoptosis);同时对 Danio rerio 胚胎和幼鱼具有高急性毒性。Fluoxastrobin 可用于茶叶叶面病害 (包括茶赤叶斑病和茶灰斑病) 的相关研究。

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Fluoxastrobin

Fluoxastrobin Chemical Structure

CAS No. : 361377-29-9

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Other Forms of Fluoxastrobin:

查看 DNA/RNA Synthesis 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fluoxastrobin is a fungicide. By binding to NAD-dependent epimerase/dehydratase, Fluoxastrobin interferes with electron transport, reduces ATP production and inhibits mycelial growth, thereby effectively controlling foliar diseases of tea plants. Fluoxastrobin induces oxidative stress by increasing ROS levels and lipid peroxidation, causes DNA damage and promotes apoptosis; meanwhile, it shows high acute toxicity to Danio rerio embryos and larvae. Fluoxastrobin can be used in research related to tea foliar diseases (including tea red leaf spot and tea gray leaf spot)[1][2].

体外研究
(In Vitro)

Fluoxastrobin (13.64 μg/mL) 可抑制拟盘多毛孢 (Pestalotiopsis trachicarpicola) 的菌丝生长,其体外半数有效浓度为 13.64 μg/mL;它可通过剂量依赖性抑制 ATP 生成并提升菌丝膜电位的方式破坏真菌能量代谢,还能与真菌 NAD 依赖型差向异构酶/脱水酶稳定结合[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Fluoxastrobin (0.03-1.0 mg/L;水体浸泡;静态,每日半静态换水;72-144 小时) 对斑马鱼胚胎表现出高急性毒性 (96 h LC50 = 0.549 mg/L),并可诱导剂量依赖性的孵化延迟、致畸性、发育损伤、氧化应激及 DNA 损伤[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

458.83

Formula

C21H16ClFN4O5

CAS 号
中文名称

氟嘧菌酯

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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