2. Gene
  3. Ano6 - anoctamin 6 Gene

Ano6 - anoctamin 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tmem16f; 2900059G15Rik; F730003B03Rik

基因 ID: 105722 | 基因类型: protein coding

关于 Ano6

功能概要

Enables gated channel activity; phospholipid scramblase activity; and protein homodimerization activity. Involved in several processes, including bleb assembly; inorganic ion transmembrane transport; and positive regulation of transport. Acts upstream of or within several processes, including bone mineralization involved in bone maturation; calcium activated phospholipid scrambling; and dendritic cell chemotaxis. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and viscerocranium. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6). [provided by Alliance of Genome Resources, Apr 2022]

Ano6 基因产物(2)

mRNA Protein Name
NM_001253813.1 NP_001240742.1 anoctamin-6 isoform 1
NM_175344.4 NP_780553.2 anoctamin-6 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-activated cation channel activity IDA
IDA: 通过直接分析推断
23021219 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
23576756 MGI
NOT enables intracellularly calcium-gated chloride channel activity IDA
IDA: 通过直接分析推断
22075693 MGI
enables intracellularly calcium-gated chloride channel activity IDA
IDA: 通过直接分析推断
20056604 MGI
enables intracellularly calcium-gated chloride channel activity IMP
IMP: 通过突变表型推断
23159814 MGI
enables phospholipid scramblase activity IDA
IDA: 通过直接分析推断
23532839 MGI
enables phospholipid scramblase activity IMP
IMP: 通过突变表型推断
23532839 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
30785399 MGI
enables voltage-gated monoatomic ion channel activity IDA
IDA: 通过直接分析推断
23021219 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bleb assembly IMP
IMP: 通过突变表型推断
25651887 MGI
involved in blood coagulation IMP
IMP: 通过突变表型推断
23021219 MGI
acts upstream of or within bone mineralization involved in bone maturation IMP
IMP: 通过突变表型推断
22936354 MGI
acts upstream of or within calcium activated galactosylceramide scrambling IDA
IDA: 通过直接分析推断
23532839 MGI
acts upstream of or within calcium activated phosphatidylcholine scrambling IDA
IDA: 通过直接分析推断
23532839 MGI
acts upstream of or within calcium activated phosphatidylserine scrambling IDA
IDA: 通过直接分析推断
23532839 MGI
acts upstream of or within calcium activated phospholipid scrambling IMP
IMP: 通过突变表型推断
22936354 MGI
involved in calcium ion transmembrane transport IGI
IGI: 通过遗传相互作用推断
25589784 MGI
involved in chloride transmembrane transport IDA
IDA: 通过直接分析推断
30785399 MGI
involved in chloride transmembrane transport IMP
IMP: 通过突变表型推断
25589784 MGI
acts upstream of or within chloride transport IDA
IDA: 通过直接分析推断
20056604 MGI
acts upstream of or within chloride transport IMP
IMP: 通过突变表型推断
23159814 MGI
acts upstream of or within dendritic cell chemotaxis IMP
IMP: 通过突变表型推断
23159814 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: 通过直接分析推断
23532839 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
22936354 MGI
involved in negative regulation of cell volume IMP
IMP: 通过突变表型推断
25651887 MGI
NOT acts upstream of or within phosphatidylserine exposure on apoptotic cell surface IMP
IMP: 通过突变表型推断
22936354 MGI
involved in phospholipid translocation IDA
IDA: 通过直接分析推断
30785399 MGI
involved in plasma membrane phospholipid scrambling IMP
IMP: 通过突变表型推断
23021219 MGI
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
25651887 MGI
involved in positive regulation of bone mineralization IMP
IMP: 通过突变表型推断
25589784 MGI
involved in positive regulation of monoatomic ion transmembrane transport IMP
IMP: 通过突变表型推断
25651887 MGI
involved in positive regulation of monocyte chemotaxis IMP
IMP: 通过突变表型推断
25651887 MGI
involved in positive regulation of phagocytosis, engulfment IMP
IMP: 通过突变表型推断
25651887 MGI
involved in purinergic nucleotide receptor signaling pathway IMP
IMP: 通过突变表型推断
25651887 MGI
involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
32101737 MGI
involved in regulation of postsynaptic membrane potential IMP
IMP: 通过突变表型推断
32101737 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cholinergic synapse IDA
IDA: 通过直接分析推断
32101737 MGI
is active in cholinergic synapse IMP
IMP: 通过突变表型推断
32101737 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
30785399 MGI
is active in synaptic membrane IDA
IDA: 通过直接分析推断
32101737 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

anoctamin-6

SCAN channel

small-conductance calcium-activated nonselective cation channel

transmembrane protein 16F

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-164139 Antiviral agent 57 Inhibitor 98.10% 否
HY-RS00746 ANO6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20248 Ano6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26756 Ano6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ano6 NCBI NCBI:196527
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