TACC2 - transforming acidic coiled-coil containing protein 2 Gene

中文名称：含转化酸性卷曲螺旋蛋白 2

种属: Homo sapiens

同用名: AZU-1; ECTACC

关于 TACC2

功能概要

转化酸性卷曲螺旋蛋白是与癌症有关的中心体和微管相互作用蛋白的保守家族。该基因编码的蛋白质在整个细胞周期中集中在中心体。该基因位于与肿瘤发生相关的染色体区域内。该基因的表达由促红细胞生成素诱导，被认为会影响乳腺肿瘤的进展。已发现该基因编码不同亚型的几种转录变体。[RefSeq 提供，2008 年 7 月]

Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in Cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]