2. Gene
  3. Cth - cystathionase (cystathionine gamma-lyase) Gene

Cth - cystathionase (cystathionine gamma-lyase) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CGL; CSE; Cys3; 0610010I13Rik

基因 ID: 107869 | 基因类型: protein coding

关于 Cth

功能概要

Enables L-cystine L-cysteine-lyase (deaminating) and cystathionine gamma-lyase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of NF-kappaB transcription factor activity; and protein sulfhydration. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and negative regulation of apoptotic signaling pathway. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; cranium; ear; and genitourinary system. Used to study cystathioninuria. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase). [provided by Alliance of Genome Resources, Apr 2022]

Cth 基因产物(2)

mRNA Protein Name
NM_145953.2 NP_666065.1 cystathionine gamma-lyase
NM_145953.2 NP_666065.1 cystathionine gamma-lyase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-cystine L-cysteine-lyase (deaminating) IDA
IDA: 通过直接分析推断
22244329 MGI
enables L-cystine L-cysteine-lyase (deaminating) IMP
IMP: 通过突变表型推断
19903941 MGI
enables cystathionine gamma-lyase activity IDA
IDA: 通过直接分析推断
15038791 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19903941 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
22244329 MGI
acts upstream of or within negative regulation of apoptotic signaling pathway IMP
IMP: 通过突变表型推断
22244329 MGI
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
22244329 MGI
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
22244329 MGI
involved in protein sulfhydration IDA
IDA: 通过直接分析推断
22244329 MGI
involved in protein sulfhydration IMP
IMP: 通过突变表型推断
19903941 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cystathionine gamma-lyase

cysteine desulfhydrase

cysteine-protein sulfhydrase

homocysteine desulfhydrase

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03296 CTH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-181717 TKL002 / 否
HY-RS15708 VSIG2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17261 Cth Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23715 Cth Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cth NCBI NCBI:1491
Rattus norvegicus Cth NCBI NCBI:24962
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