1. Gene
  2. CTH - Cth cystathionine gamma-lyase Gene

CTH - Cth cystathionine gamma-lyase Gene

种属: Rattus norvegicus

同用名: CGL; CSE

基因 ID: 24962 | 基因类型: protein coding

关于 CTH

功能概要

Enables cystathionine beta-lyase activity. Involved in several processes, including alpha-amino acid metabolic process; glutathione metabolic process; and negative regulation of cell growth. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Used to study cataract. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase). [provided by Alliance of Genome Resources, Apr 2022]

基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glutathione metabolic process IMP
IMP: 通过突变表型推断
15683713 RGD
involved in negative regulation of cell growth IMP
IMP: 通过突变表型推断
15347670 RGD
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15347670 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cystathionine gamma-lyase

CTL target antigen

PRB-RA

cystathionase (cystathionine gamma-lyase)

cysteine desulfhydrase

cysteine-protein sulfhydrase

gamma-cystathionase

homocysteine desulfhydrase

probasin-related antigen

直系同源

种属 基因名 来源 基因 ID
Homo sapiens CTH NCBI NCBI:1491
Mus musculus CTH NCBI NCBI:107869