1. Gene
  2. CHAD - chondroadherin Gene

CHAD - chondroadherin Gene

中文名称:软骨粘附素

种属: Homo sapiens

同用名: SLRR4A

基因 ID: 1101 | 基因类型: protein coding

关于 CHAD

Cytogenetic location: 17q21.33 Genomic coordinates (GRCh38): 17:50,464,496-50,468,880 (from NCBI)

This gene has 3 transcripts (splice variants), 167 orthologues and 22 paralogues. Broad expression in small intestine (RPKM 4.5), liver (RPKM 4.4) and 24 other tissues.

功能概要

软骨粘附素是一种软骨基质蛋白,被认为可介导分离的软骨细胞的粘附。该蛋白质包含 11 个富含亮氨酸的重复序列,两侧是富含半胱氨酸的区域。软骨粘附素信使 RNA 存在于所有年龄段的软骨细胞中。[RefSeq 提供,2008 年 7 月]

Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. The protein contains 11 leucine-rich repeats flanked by cysteine-rich regions. The chondroadherin messenger RNA is present in chondrocytes at all ages. [provided by RefSeq, Jul 2008]

CHAD 基因产物(1)

mRNA Protein Name
NM_001267.3 NP_001258.2 chondroadherin precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CHAD 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (22 - 48)

LRR_6

LRR_6: Leucine Rich repeat (74 - 90)

LRR_8

LRR_8: Leucine rich repeat (101 - 159)

LRR_8

LRR_8: Leucine rich repeat (196 - 241)

LRR_1

LRR_1: Leucine Rich Repeat (270 - 287)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
蛋白主名 其他名称

chondroadherin

cartilage leucine-rich protein

CHAD 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CHAD O15335 CNPY4 Homo sapiens Q8N129 28514442
种属内
CHAD O15335 CNPY4 Homo sapiens Q8N129 33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Epilepsy, Idiopathic Generalized 17

Febrile Seizures, Familial, 2

EIG17

Familial Febrile Seizures 2

FEB2

Epilepsy, Idiopathic Generalized, Susceptibility To, 17

Familial Febrile Convulsions 2

Convulsions, Familial Febrile, 2

Calcific Tendinitis

Calcific Tendinitis Nos

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus CHAD VGNC VGNC:27264
Rattus norvegicus CHAD RGD RGD:2336
Macaca mulatta CHAD VGNC VGNC:71023
Felis catus CHAD VGNC VGNC:60834
Canis familiaris CHAD VGNC VGNC:39187
Mus musculus CHAD MGD MGI:1096866
Others CHAD NCBI