2. Gene
  3. IFTAP - intraflagellar transport associated protein Gene

IFTAP - intraflagellar transport associated protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：鞭毛内转运相关蛋白

种属: Homo sapiens

同用名: NWC; HEPIS; C11orf74

基因 ID: 119710 | 基因类型: protein coding

关于 IFTAP

Cytogenetic location: 11p12 Genomic coordinates (GRCh38): 11:36,594,502-36,659,272 (from NCBI)

This gene has 27 transcripts (splice variants) and 123 orthologues. Broad expression in thyroid (RPKM 26.2), testis (RPKM 16.8) and 22 other tissues.

功能概要

该基因编码的蛋白质被确定为严重急性呼吸系统综合症冠状病毒 (SARS-CoV) 非结构蛋白 10 的细胞相互作用伙伴。所编码的蛋白质可作为转录的负调节因子发挥作用。该基因在 1 号染色体上有一个假基因。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 3 月]

This gene encodes a protein that was identified as a cellular interacting partner of non-structural protein 10 of the severe acute respiratory syndrome coronavirus (SARS-CoV). The encoded protein may function as a negative regulator of transcription. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

IFTAP 基因产物(7)

mRNA Protein Name
NM_001276722.2 NP_001263651.1 intraflagellar transport-associated protein isoform a
NM_001276723.2 NP_001263652.1 intraflagellar transport-associated protein isoform a
NM_001276724.2 NP_001263653.1 intraflagellar transport-associated protein isoform a
NM_001276725.2 NP_001263654.1 intraflagellar transport-associated protein isoform b
NM_001276726.2 NP_001263655.1 intraflagellar transport-associated protein isoform b
NM_001276727.2 NP_001263656.1 intraflagellar transport-associated protein isoform b
NM_138787.4 NP_620142.2 intraflagellar transport-associated protein isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables intraciliary transport particle A binding IDA
IDA: 通过直接分析推断
30476139 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
18433331 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

intraflagellar transport-associated protein

protein C11orf74

IFTAP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
IFTAP Q86VG3 BTF3 Homo sapiens P20290
Anti Bait CoIP
18433331
种属内
IFTAP Q86VG3 BTF3 Homo sapiens P20290
Y2H
18433331
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Cranioectodermal Dysplasia 1

Sensenbrenner Syndrome

CED1

Levin Syndrome I

Cranio-Ectodermal Dysplasia

Dysplasia, Cranioectodermal, Type 1

Cranioectodermal Dysplasia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06611 IFTAP Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus IFTAP VGNC VGNC:52633
Felis catus IFTAP VGNC VGNC:81987
Mus musculus IFTAP MGD MGI:1915420
Canis familiaris IFTAP VGNC VGNC:51850
Macaca mulatta IFTAP VGNC VGNC:70379
Rattus norvegicus IFTAP RGD RGD:1309730
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